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    Anp32a acidic nuclear phosphoprotein 32 family member A [ Mus musculus (house mouse) ]

    Gene ID: 11737, updated on 9-Dec-2024

    Summary

    Official Symbol
    Anp32aprovided by MGI
    Official Full Name
    acidic nuclear phosphoprotein 32 family member Aprovided by MGI
    Primary source
    MGI:MGI:108447
    See related
    Ensembl:ENSMUSG00000032249 AllianceGenome:MGI:108447
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LANP; pp32; Anp32; PHAP1; I1PP2A
    Summary
    Predicted to enable histone binding activity. Predicted to be involved in nucleocytoplasmic transport and regulation of apoptotic process. Located in nuclear matrix. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to several human genes including ANP32A (acidic nuclear phosphoprotein 32 family member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 178.7), CNS E14 (RPKM 62.2) and 15 other tissues See more
    Orthologs
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    Genomic context

    See Anp32a in Genome Data Viewer
    Location:
    9 B; 9 33.68 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (62248637..62286084)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (62341343..62378804)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 pseudogene Neighboring gene predicted gene, 35288 Neighboring gene STARR-seq mESC enhancer starr_24372 Neighboring gene STARR-positive B cell enhancer ABC_E6749 Neighboring gene predicted gene, 20346 Neighboring gene predicted gene, 40522 Neighboring gene STARR-seq mESC enhancer starr_24378 Neighboring gene VISTA enhancer mm210 Neighboring gene predicted gene, 40523

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables histone binding  
    enables protein binding PubMed 
    Process Evidence Code Pubs
    involved_in nucleocytoplasmic transport  
    involved_in regulation of apoptotic process  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytoplasm  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    located_in nuclear matrix PubMed 
    is_active_in nucleus  
    located_in nucleus PubMed 
    located_in nucleus  
    is_active_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  

    General protein information

    Preferred Names
    acidic leucine-rich nuclear phosphoprotein 32 family member A
    Names
    acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
    acidic nuclear phosphoprotein 32
    acidic nuclear phosphoprotein pp32
    leucine-rich acidic nuclear protein
    potent heat-stable protein phosphatase 2A inhibitor I1PP2A
    vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411151.1NP_001398080.1  acidic leucine-rich nuclear phosphoprotein 32 family member A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC113291, AC121813
    2. NM_001411152.1NP_001398081.1  acidic leucine-rich nuclear phosphoprotein 32 family member A isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC113291, AC121813
      UniProtKB/TrEMBL
      D3Z7M9
      Related
      ENSMUSP00000122165.2, ENSMUST00000135395.8
    3. NM_009672.4NP_033802.2  acidic leucine-rich nuclear phosphoprotein 32 family member A isoform 1

      See identical proteins and their annotated locations for NP_033802.2

      Status: VALIDATED

      Source sequence(s)
      AC113291, AC121813
      Consensus CDS
      CCDS40663.1
      UniProtKB/Swiss-Prot
      O35381, P97437
      Related
      ENSMUSP00000082652.7, ENSMUST00000085519.13
      Conserved Domains (3) summary
      sd00035
      Location:90113
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam14580
      Location:71146
      LRR_9; Leucine-rich repeat
      NF033189
      Location:9128
      internalin_A; class 1 internalin InlA

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      62248637..62286084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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