Zfp764 zinc finger protein 764 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp764provided by MGI
Official Full Name: zinc finger protein 764provided by MGI
Primary source: MGI:MGI:2443580
See related: Ensembl:ENSMUSG00000045757 AllianceGenome:MGI:2443580
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 8030466O12Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coregulator activity. Predicted to be involved in cellular response to glucocorticoid stimulus and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; genitourinary system; heart; and limb. Orthologous to human ZNF764 (zinc finger protein 764). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in large intestine adult (RPKM 1.7), lung adult (RPKM 1.7) and 28 other tissues See more
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Genomic context

Location:: 7 F3; 7 69.5 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (126975978..127006005, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (127379762..127406835, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to glucocorticoid stimulus	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger protein 764

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001167832.1 → NP_001161304.1 zinc finger protein 764 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, compared to variant 1. This difference results in a frameshift and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.

Source sequence(s)

AK042873, AK053795

UniProtKB/TrEMBL

Q8C964

Related

ENSMUST00000139118.2

Conserved Domains (1) summary

pfam01352
Location:22 → 49

KRAB; KRAB box
NM_146203.4 → NP_666315.3 zinc finger protein 764 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform 1.

Source sequence(s)

AK042873, AK053795

Consensus CDS

CCDS21865.1

UniProtKB/TrEMBL

E9QAP1, Q8C964

Related

ENSMUSP00000052944.7, ENSMUST00000059199.7

Conserved Domains (6) summary

smart00349
Location:22 → 81

KRAB; krueppel associated box

COG5048
Location:178 → 243

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:154 → 174

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:321 → 343

zf-C2H2; Zinc finger, C2H2 type

pfam01352
Location:22 → 55

KRAB; KRAB box

pfam13465
Location:335 → 360

zf-H2C2_2; Zinc-finger double domain