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    Zfp738 zinc finger protein 738 [ Mus musculus (house mouse) ]

    Gene ID: 408068, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zfp738provided by MGI
    Official Full Name
    zinc finger protein 738provided by MGI
    Primary source
    MGI:MGI:3040706
    See related
    Ensembl:ENSMUSG00000048280 AllianceGenome:MGI:3040706
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3830402I07Rik; 6720487G11Rik
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF729 (zinc finger protein 729). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 2.4), CNS E14 (RPKM 2.2) and 23 other tissues See more
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    Genomic context

    See Zfp738 in Genome Data Viewer
    Location:
    13 B3; 13 34.66 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67815560..67831631, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67667441..67683512, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34905 Neighboring gene zinc finger protein 729a Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67738709-67738896 Neighboring gene STARR-seq mESC enhancer starr_34906 Neighboring gene predicted gene, 46439 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67784456-67784643 Neighboring gene zinc finger protein 65 Neighboring gene STARR-seq mESC enhancer starr_34907 Neighboring gene STARR-seq mESC enhancer starr_34908 Neighboring gene zinc finger protein 85, opposite strand Neighboring gene STARR-seq mESC enhancer starr_34909 Neighboring gene STARR-seq mESC enhancer starr_34910 Neighboring gene zinc finger protein 85

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 738
    Names
    Novel Zinc finger, C2H2 type containing protein (3830402I07Rik)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001187.3NP_001001187.2  zinc finger protein 738

      Status: VALIDATED

      Source sequence(s)
      BC082605, BY752525
      Consensus CDS
      CCDS36716.2
      UniProtKB/TrEMBL
      B8JJX8
      Related
      ENSMUSP00000121275.3, ENSMUST00000137496.10
      Conserved Domains (5) summary
      smart00349
      Location:1573
      KRAB; krueppel associated box
      COG5048
      Location:257642
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:485505
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1554
      KRAB; KRAB box
      pfam13465
      Location:497522
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      67815560..67831631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175676.2: Suppressed sequence

      Description
      NM_175676.2: This RefSeq was permanently suppressed because the CDS was partial.