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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_007082.2 RefSeqGene
- Range
-
4963..88903
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001322033.2 → NP_001308962.1 alpha-actinin-4 isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC008649, AC022144, BM841805, HY048627, R66605
- Consensus CDS
-
CCDS92611.1
- UniProtKB/TrEMBL
- A0A8V8TL71, H7C144
- Related
- ENSP00000398393.2, ENST00000440400.3
- Conserved Domains (5) summary
-
- COG5126
Location:762 → 866
- FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
- cd00176
Location:414 → 640
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam08726
Location:836 → 902
- EFhand_Ca_insen; Ca2+ insensitive EF hand
- cd21214
Location:47 → 151
- CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
- cd21216
Location:155 → 269
- CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
-
NM_001411143.1 → NP_001398072.1 alpha-actinin-4 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC008649, AC022144
- Consensus CDS
-
CCDS92610.1
- UniProtKB/TrEMBL
- A0A8V8TL71, F5GXS2
- Related
- ENSP00000411187.4, ENST00000424234.7
-
NM_004924.6 → NP_004915.2 alpha-actinin-4 isoform 1
See identical proteins and their annotated locations for NP_004915.2
Status: REVIEWED
- Source sequence(s)
-
AC022144, BC005033, BM841805, HY048627, R66605
- Consensus CDS
-
CCDS12518.1
- UniProtKB/Swiss-Prot
- A4K467, D6PXK4, O43707, O76048
- UniProtKB/TrEMBL
- A0A0S2Z3G9, A0A8V8TL71
- Related
- ENSP00000252699.2, ENST00000252699.7
- Conserved Domains (5) summary
-
- PTZ00184
Location:759 → 868
- PTZ00184; calmodulin; Provisional
- cd00176
Location:414 → 640
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam08726
Location:841 → 907
- EFhand_Ca_insen; Ca2+ insensitive EF hand
- cd21214
Location:47 → 151
- CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
- cd21216
Location:155 → 269
- CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
38647649..38731589
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017027331.3 → XP_016882820.1 alpha-actinin-4 isoform X2
- UniProtKB/TrEMBL
-
A0A8V8TL71
- Conserved Domains (5) summary
-
- PTZ00184
Location:759 → 890
- PTZ00184; calmodulin; Provisional
- cd00176
Location:414 → 640
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam08726
Location:863 → 929
- EFhand_Ca_insen; Ca2+ insensitive EF hand
- cd21214
Location:47 → 151
- CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
- cd21216
Location:155 → 269
- CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
-
XM_005259281.6 → XP_005259338.1 alpha-actinin-4 isoform X1
See identical proteins and their annotated locations for XP_005259338.1
- UniProtKB/TrEMBL
-
A0A8V8TL71
- Conserved Domains (5) summary
-
- COG5126
Location:762 → 866
- FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
- cd00176
Location:414 → 640
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam08726
Location:836 → 902
- EFhand_Ca_insen; Ca2+ insensitive EF hand
- cd21214
Location:47 → 151
- CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
- cd21216
Location:155 → 269
- CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
Reference GRCh38.p14 PATCHES
Genomic
-
NW_014040929.1 Reference GRCh38.p14 PATCHES
- Range
-
57285..141225
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054331975.1 → XP_054187950.1 alpha-actinin-4 isoform X2
- UniProtKB/TrEMBL
-
A0A8V8TL71
-
XM_054331974.1 → XP_054187949.1 alpha-actinin-4 isoform X1
- UniProtKB/TrEMBL
-
A0A8V8TL71
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
41451629..41535643
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054322244.1 → XP_054178219.1 alpha-actinin-4 isoform X2
- UniProtKB/TrEMBL
-
A0A8V8TL71
-
XM_054322243.1 → XP_054178218.1 alpha-actinin-4 isoform X1
- UniProtKB/TrEMBL
-
A0A8V8TL71