Gprasp3 G protein-coupled receptor associated sorting protein family member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gprasp3provided by RGD
Official Full Name: G protein-coupled receptor associated sorting protein family member 3provided by RGD
Primary source: RGD:1303224
See related: EnsemblRapid:ENSRNOG00000003191 AllianceGenome:RGD:1303224
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Bhlhb9; KKPROT; p60TRP
Summary: Predicted to enable protein homodimerization activity. Predicted to be involved in learning or memory; negative regulation of neuron apoptotic process; and positive regulation of nervous system development. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including GPRASP3 (G protein-coupled receptor associated sorting protein family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 78.8), Kidney (RPKM 58.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq32

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (103639366..103644561)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (98847591..98854949)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (106359981..106393457)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in learning or memory	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of neuron apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of dendritic spine morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neurogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synapse assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: G protein-coupled receptor associated sorting protein 3

Names: basic helix-loop-helix domain containing, class B, 9; basic helix-loop-helix family member B9; protein BHLHB9; transcription regulator of 60 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.