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    Cfap46 cilia and flagella associated protein 46 [ Mus musculus (house mouse) ]

    Gene ID: 212124, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cfap46provided by MGI
    Official Full Name
    cilia and flagella associated protein 46provided by MGI
    Primary source
    MGI:MGI:2444387
    See related
    Ensembl:ENSMUSG00000049571 AllianceGenome:MGI:2444387
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm170; Ttc40; 9330101J02Rik; E030019B06Rik
    Summary
    Orthologous to human CFAP46 (cilia and flagella associated protein 46). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 9.4), lung adult (RPKM 1.3) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cfap46 in Genome Data Viewer
    Location:
    7 F4; 7 84.57 cM
    Exon count:
    60
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (139180830..139264701, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (139600914..139684787, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene glycosylated lysosomal membrane protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_20426 Neighboring gene STARR-seq mESC enhancer starr_20427 Neighboring gene predicted gene, 33031 Neighboring gene NK6 homeobox 2 Neighboring gene STARR-positive B cell enhancer mm9_chr7:146833912-146834213 Neighboring gene STARR-seq mESC enhancer starr_20429 Neighboring gene STARR-positive B cell enhancer mm9_chr7:146870578-146870879 Neighboring gene NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 pseudogene Neighboring gene predicted gene, 32680 Neighboring gene ribosomal protein L21-ps13 Neighboring gene STARR-seq mESC enhancer starr_20430 Neighboring gene STARR-seq mESC enhancer starr_20432 Neighboring gene ribosomal protein L24 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    cilia- and flagella-associated protein 46
    Names
    cilia and flagella protein 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001302546.1 → NP_001289475.1  cilia- and flagella-associated protein 46

      Status: VALIDATED

      Source sequence(s)
      AC112670, AC141643, AK033851
      Consensus CDS
      CCDS57592.2
      UniProtKB/TrEMBL
      E9Q2C0
      Related
      ENSMUSP00000120186.3, ENSMUST00000129990.9

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      139180830..139264701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322097.3 → XP_017177586.1  cilia- and flagella-associated protein 46 isoform X1

      UniProtKB/TrEMBL
      Q8BZQ3

    2. XM_036152877.1 → XP_036008770.1  cilia- and flagella-associated protein 46 isoform X2

      UniProtKB/TrEMBL
      Q8BZQ3

    3. XM_017322099.3 → XP_017177588.1  cilia- and flagella-associated protein 46 isoform X3

      UniProtKB/TrEMBL
      Q8BZQ3

    4. XM_017322100.2 → XP_017177589.1  cilia- and flagella-associated protein 46 isoform X4

      UniProtKB/TrEMBL
      Q8BZQ3

    5. XM_017322101.1 → XP_017177590.1  cilia- and flagella-associated protein 46 isoform X5

      UniProtKB/TrEMBL
      Q8BZQ3

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001243018.1: Suppressed sequence

      Description
      NM_001243018.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    2. NM_177212.2: Suppressed sequence

      Description
      NM_177212.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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