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    Or1p1 olfactory receptor family 1 subfamily P member 1 [ Mus musculus (house mouse) ]

    Gene ID: 18359, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or1p1provided by MGI
    Official Full Name
    olfactory receptor family 1 subfamily P member 1provided by MGI
    Primary source
    MGI:MGI:1333755
    See related
    Ensembl:ENSMUSG00000070374 AllianceGenome:MGI:1333755
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IH3; Olfr59; MOR133-3P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or1p1 in Genome Data Viewer
    Location:
    11 B5; 11 45.76 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (74174562..74180472)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (74283736..74289646)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily P member 1C Neighboring gene olfactory receptor family 1 subfamily A member 7, pseudogene 1 Neighboring gene olfactory receptor family 1 subfamily A member 6, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_29950 Neighboring gene olfactory receptor family 1 subfamily P member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article
    2. Identification of ligands for olfactory receptors by functional expression of a receptor library. Krautwurst D, et al. Cell, 1998 Dec 23. PMID 9875846
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 59
    Names
    GA_x6K02T2P1NL-4434429-4435400
    olfactory receptor MOR133-3P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362665.1 → NP_001349594.1  olfactory receptor 59

      Status: VALIDATED

      Source sequence(s)
      AL604065
      Consensus CDS
      CCDS25029.1
      UniProtKB/TrEMBL
      B1ARL2, B1ARL3, Q7TRW9
      Related
      ENSMUSP00000119877.3, ENSMUST00000143976.4
      Conserved Domains (1) summary
      cd15918
      Location:25 → 296
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. NM_011002.3 → NP_035132.2  olfactory receptor 59

      See identical proteins and their annotated locations for NP_035132.2

      Status: VALIDATED

      Source sequence(s)
      AL604065
      Consensus CDS
      CCDS25029.1
      UniProtKB/TrEMBL
      B1ARL2, B1ARL3, Q7TRW9
      Related
      ENSMUSP00000148959.3, ENSMUST00000214048.3
      Conserved Domains (1) summary
      cd15918
      Location:25 → 296
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      74174562..74180472
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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