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    Cytip cytohesin 1 interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 227929, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cytipprovided by MGI
    Official Full Name
    cytohesin 1 interacting proteinprovided by MGI
    Primary source
    MGI:MGI:2183535
    See related
    Ensembl:ENSMUSG00000026832 AllianceGenome:MGI:2183535
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cbp; Cybr; Pscdbp; A130053M09Rik
    Summary
    Predicted to be involved in regulation of cell adhesion. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cell cortex. Is expressed in metanephros. Orthologous to human CYTIP (cytohesin 1 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in thymus adult (RPKM 15.2), spleen adult (RPKM 14.5) and 6 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cytip in Genome Data Viewer
    Location:
    2 C1.1; 2 33.05 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (58019151..58085559, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (58129139..58195549, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_04539 Neighboring gene ermin, ERM-like protein Neighboring gene polypeptide N-acetylgalactosaminyltransferase 5 Neighboring gene STARR-positive B cell enhancer mm9_chr2:57882224-57882524 Neighboring gene STARR-seq mESC enhancer starr_04540 Neighboring gene STARR-positive B cell enhancer ABC_E3374 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 15 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2036 Neighboring gene STARR-positive B cell enhancer ABC_E1589 Neighboring gene STARR-positive B cell enhancer ABC_E3375 Neighboring gene STARR-positive B cell enhancer ABC_E5917 Neighboring gene STARR-positive B cell enhancer ABC_E5918 Neighboring gene STARR-positive B cell enhancer ABC_E7817 Neighboring gene STARR-positive B cell enhancer ABC_E5919 Neighboring gene STARR-positive B cell enhancer ABC_E3376 Neighboring gene STARR-seq mESC enhancer starr_04541 Neighboring gene predicted gene 13546 Neighboring gene STARR-positive B cell enhancer mm9_chr2:58049102-58049403 Neighboring gene STARR-seq mESC enhancer starr_04542 Neighboring gene STARR-positive B cell enhancer mm9_chr2:58134871-58135172 Neighboring gene activin A receptor, type IC Neighboring gene predicted gene 13544 Neighboring gene 60S ribosomal protein L29 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cytohesin-interacting protein
    Names
    cbp HE
    cytohesin binding protein
    cytohesin-binding protein HE
    pleckstrin homology, Sec7 and coiled-coil domains, binding protein
    tamalin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139200.4NP_631939.1  cytohesin-interacting protein

      See identical proteins and their annotated locations for NP_631939.1

      Status: VALIDATED

      Source sequence(s)
      AK152784, AK157859, AL928564
      Consensus CDS
      CCDS16048.1
      UniProtKB/Swiss-Prot
      A2AS77, Q3TZH1, Q8R4T4, Q91VY6, Q9QZA9
      UniProtKB/TrEMBL
      Q3TCC3, Q3TLX8
      Related
      ENSMUSP00000028175.7, ENSMUST00000028175.7
      Conserved Domains (1) summary
      cd00992
      Location:76161
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      58019151..58085559 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498012.5XP_006498075.1  cytohesin-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006498075.1

      UniProtKB/Swiss-Prot
      A2AS77, Q3TZH1, Q8R4T4, Q91VY6, Q9QZA9
      UniProtKB/TrEMBL
      Q3TCC3, Q3TLX8
      Conserved Domains (1) summary
      cd00992
      Location:76161
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. XM_006498013.3XP_006498076.1  cytohesin-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006498076.1

      UniProtKB/Swiss-Prot
      A2AS77, Q3TZH1, Q8R4T4, Q91VY6, Q9QZA9
      UniProtKB/TrEMBL
      Q3TCC3, Q3TLX8
      Conserved Domains (1) summary
      cd00992
      Location:76161
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...