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    Spmap2 sperm microtubule associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 21830, updated on 9-Dec-2024

    Summary

    Official Symbol
    Spmap2provided by MGI
    Official Full Name
    sperm microtubule associated protein 2provided by MGI
    Primary source
    MGI:MGI:1338756
    See related
    Ensembl:ENSMUSG00000020317 AllianceGenome:MGI:1338756
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Theg
    Summary
    Acts upstream of or within spermatogenesis. Predicted to be located in cytoplasm. Is expressed in large intestine; metanephros; ovary; submandibular gland; and testis. Orthologous to human SPMAP2 (sperm microtubule associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 111.0) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Spmap2 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79412311..79422970, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79576477..79587136, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 2 Neighboring gene microRNA 6909 Neighboring gene MIER family member 2 Neighboring gene predicted gene, 51808 Neighboring gene C2 calcium-dependent domain containing 4C Neighboring gene SHC (Src homology 2 domain containing) transforming protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sperm microtubule associated protein 2
    Names
    testicular haploid expressed gene product
    testicular haploid expressed gene protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428846.1NP_001415775.1  sperm microtubule associated protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132265
    2. NM_011583.4NP_035713.1  sperm microtubule associated protein 2 isoform 1

      See identical proteins and their annotated locations for NP_035713.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC132265
      Consensus CDS
      CCDS23977.1
      UniProtKB/Swiss-Prot
      Q6P8H9, Q9JMB1, Q9QZ27
      Related
      ENSMUSP00000020566.7, ENSMUST00000020566.7
      Conserved Domains (1) summary
      pfam14912
      Location:209267
      THEG; Testicular haploid expressed repeat
    3. NM_199226.2NP_954696.1  sperm microtubule associated protein 2 isoform 2

      See identical proteins and their annotated locations for NP_954696.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment in the N-terminal region, compared to isoform 1.
      Source sequence(s)
      AC132265
      Consensus CDS
      CCDS23978.1
      UniProtKB/Swiss-Prot
      Q9JMB1
      Related
      ENSMUSP00000076647.7, ENSMUST00000077433.13
      Conserved Domains (1) summary
      pfam14912
      Location:185243
      THEG; Testicular haploid expressed repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      79412311..79422970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513579.3XP_006513642.1  sperm microtubule associated protein 2 isoform X1

      Conserved Domains (1) summary
      pfam14912
      Location:212267
      THEG; Testicular haploid expressed repeat