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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_016205.3 → NP_057289.1 platelet-derived growth factor C precursor
See identical proteins and their annotated locations for NP_057289.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the shorter transcript and encodes the functional protein.
- Source sequence(s)
-
AC092608, AC093325, AF091434, AI446155
- Consensus CDS
-
CCDS3795.1
- UniProtKB/Swiss-Prot
- B4DU34, B9EGR8, Q4W5M9, Q9NRA1, Q9UL22
- UniProtKB/TrEMBL
-
B2R9K6
- Related
- ENSP00000422464.1, ENST00000502773.6
- Conserved Domains (2) summary
-
- cd00041
Location:49 → 162
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- cd00135
Location:248 → 340
- PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
RNA
-
NR_036641.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, also known as PDGF-Cb) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC092608, AC093325, AF091434, AI446155, AM922296