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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029714.2 RefSeqGene
- Range
-
16326..106531
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_604
mRNA and Protein(s)
-
NM_001032281.4 → NP_001027452.1 tissue factor pathway inhibitor isoform b precursor
See identical proteins and their annotated locations for NP_001027452.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (b, also known as TFPIbeta) has a shorter and distinct C-terminus, which includes a glycosylphosphatidylinositol (GPI) anchor attachment site, compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
- Source sequence(s)
-
AF021834, BC015514, HY175080
- Consensus CDS
-
CCDS33349.1
- UniProtKB/Swiss-Prot
-
P10646
- Related
- ENSP00000342306.4, ENST00000339091.8
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:53 → 104
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
-
NM_001318941.3 → NP_001305870.1 tissue factor pathway inhibitor isoform b precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (b, also known as TFPIbeta) has a shorter and distinct C-terminus, which includes a glycosylphosphatidylinositol (GPI) anchor attachment site, compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
- Source sequence(s)
-
AF021834, BC015514, HY175080
- Consensus CDS
-
CCDS33349.1
- UniProtKB/Swiss-Prot
-
P10646
- Related
- ENSP00000386344.1, ENST00000409676.5
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:53 → 104
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
-
NM_001329239.2 → NP_001316168.1 tissue factor pathway inhibitor isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1 but encodes the same isoform (a, also known as TFPIalpha), which is secreted. Variants 1 and 4-6 encode the same isoform (a).
- Source sequence(s)
-
AC007319, AC098485, CA418214
- Consensus CDS
-
CCDS2294.1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:216 → 268
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
-
NM_001329240.2 → NP_001316169.1 tissue factor pathway inhibitor isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1 but encodes the same isoform (a, also known as TFPIalpha), which is secreted. Variants 1 and 4-6 encode the same isoform (a).
- Source sequence(s)
-
AC007319, AC098485, CA418214
- Consensus CDS
-
CCDS2294.1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
- Related
- ENSP00000376172.1, ENST00000392365.5
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:216 → 268
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
-
NM_001329241.2 → NP_001316170.1 tissue factor pathway inhibitor isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1 but encodes the same isoform (a, also known as TFPIalpha), which is secreted. Variants 1 and 4-6 encode the same isoform (a).
- Source sequence(s)
-
AC007319, AC098485, CA418214
- Consensus CDS
-
CCDS2294.1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:216 → 268
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
-
NM_006287.6 → NP_006278.1 tissue factor pathway inhibitor isoform a precursor
See identical proteins and their annotated locations for NP_006278.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (a, also known as TFPIalpha), which is secreted. Variants 1 and 4-6 encode the same isoform (a).
- Source sequence(s)
-
AC007319, CA418214, HY175080, J03225
- Consensus CDS
-
CCDS2294.1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
- Related
- ENSP00000233156.3, ENST00000233156.9
- Conserved Domains (2) summary
-
- cd00109
Location:123 → 175
- KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
- pfam00014
Location:216 → 268
- Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
187464230..187554435 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047445619.1 → XP_047301575.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445620.1 → XP_047301576.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445621.1 → XP_047301577.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445618.1 → XP_047301574.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445617.1 → XP_047301573.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445622.1 → XP_047301578.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_047445623.1 → XP_047301579.1 tissue factor pathway inhibitor isoform X2
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
187953180..188043364 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054343583.1 → XP_054199558.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_054343584.1 → XP_054199559.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_054343585.1 → XP_054199560.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_054343582.1 → XP_054199557.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_054343581.1 → XP_054199556.1 tissue factor pathway inhibitor isoform X1
- UniProtKB/Swiss-Prot
- O95103, P10646, Q53TS4
- UniProtKB/TrEMBL
-
B2R8Y9
-
XM_054343586.1 → XP_054199561.1 tissue factor pathway inhibitor isoform X2