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    Ccdc73 coiled-coil domain containing 73 [ Mus musculus (house mouse) ]

    Gene ID: 211936, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ccdc73provided by MGI
    Official Full Name
    coiled-coil domain containing 73provided by MGI
    Primary source
    MGI:MGI:3606488
    See related
    Ensembl:ENSMUSG00000045106 AllianceGenome:MGI:3606488
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4931417A20; 2210415I11Rik
    Summary
    Orthologous to human CCDC73 (coiled-coil domain containing 73). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 2.4), frontal lobe adult (RPKM 1.9) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc73 in Genome Data Viewer
    Location:
    2 E2; 2 55.0 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (104716669..104830082)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (104886324..104999737)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene TAR DNA binding protein pseudogene Neighboring gene proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) Neighboring gene STARR-positive B cell enhancer ABC_E7844 Neighboring gene STARR-seq mESC enhancer starr_05298 Neighboring gene STARR-positive B cell enhancer mm9_chr2:104728128-104728428 Neighboring gene STARR-positive B cell enhancer mm9_chr2:104828551-104828851 Neighboring gene eukaryotic translation initiation factor 3, subunit M Neighboring gene predicted gene, 38521 Neighboring gene NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Khan M, et al. Sci Rep, 2018 Mar 21. PMID 29563520, Free PMC Article
    2. Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation. Cidad P, et al. J Cell Physiol, 2021 Jun. PMID 33230847
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 73

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177600.4 → NP_808268.2  coiled-coil domain-containing protein 73

      Status: VALIDATED

      Source sequence(s)
      AK029862, AL606494, BB615231, BC095976
      Consensus CDS
      CCDS16494.2
      UniProtKB/Swiss-Prot
      A2A6Z9, Q501M4, Q8CDM4
      Related
      ENSMUSP00000106743.2, ENSMUST00000111114.8
      Conserved Domains (1) summary
      pfam15818
      Location:28 → 1059
      CCDC73; Coiled-coil domain-containing protein 73 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      104716669..104830082
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CDM4.2 GenPept UniProtKB/Swiss-Prot:Q8CDM4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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