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    Zfp697 zinc finger protein 697 [ Mus musculus (house mouse) ]

    Gene ID: 242109, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp697provided by MGI
    Official Full Name
    zinc finger protein 697provided by MGI
    Primary source
    MGI:MGI:2139736
    See related
    Ensembl:ENSMUSG00000050064 AllianceGenome:MGI:2139736
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf697; 9430053K19
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system and genitourinary system. Orthologous to human ZNF697 (zinc finger protein 697). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 3.6), lung adult (RPKM 3.4) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp697 in Genome Data Viewer
    Location:
    3 F2.2; 3 42.75 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (98289278..98508893)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (98381962..98431951)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4565 Neighboring gene STARR-positive B cell enhancer ABC_E11203 Neighboring gene STARR-positive B cell enhancer ABC_E7932 Neighboring gene 3-phosphoglycerate dehydrogenase Neighboring gene predicted gene, 31420 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:98210571-98210772 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 9 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 pseudogene Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 pseudogene Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 8 Neighboring gene predicted gene 5853 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_08480 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 697

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411512.1 → NP_001398441.1  zinc finger protein 697 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC161053
      UniProtKB/TrEMBL
      G5E8C0

    2. NM_001411514.1 → NP_001398443.1  zinc finger protein 697 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC161053
      UniProtKB/TrEMBL
      G5E8C0

    3. NM_001411515.1 → NP_001398444.1  zinc finger protein 697 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC161053

    4. NM_172863.5 → NP_766451.3  zinc finger protein 697 isoform 1

      See identical proteins and their annotated locations for NP_766451.3

      Status: VALIDATED

      Source sequence(s)
      AC161053
      Consensus CDS
      CCDS38564.1
      UniProtKB/TrEMBL
      G5E8C0
      Related
      ENSMUSP00000056979.9, ENSMUST00000056096.15
      Conserved Domains (2) summary
      COG5048
      Location:388 → 569
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:463 → 483
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      98289278..98508893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252619.1 → XP_030108479.1  zinc finger protein 697 isoform X1

      UniProtKB/TrEMBL
      G5E8C0
      Conserved Domains (2) summary
      COG5048
      Location:388 → 569
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:463 → 483
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_030252617.1 → XP_030108477.1  zinc finger protein 697 isoform X1

      UniProtKB/TrEMBL
      G5E8C0
      Conserved Domains (2) summary
      COG5048
      Location:388 → 569
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:463 → 483
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_006501480.3 → XP_006501543.1  zinc finger protein 697 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:369 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:444 → 464
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_036163104.1 → XP_036018997.1  zinc finger protein 697 isoform X3

      Conserved Domains (3) summary
      COG5082
      Location:374 → 443
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
      pfam14787
      Location:408 → 439
      zf-CCHC_5; GAG-polyprotein viral zinc-finger
      pfam00607
      Location:164 → 353
      Gag_p24; gag gene protein p24 (core nucleocapsid protein)

    5. XM_030252618.1 → XP_030108478.1  zinc finger protein 697 isoform X1

      UniProtKB/TrEMBL
      G5E8C0
      Conserved Domains (2) summary
      COG5048
      Location:388 → 569
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:463 → 483
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q569E7.1 GenPept UniProtKB/Swiss-Prot:Q569E7

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