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    Cldn34b2 claudin 34B2 [ Mus musculus (house mouse) ]

    Gene ID: 73347, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cldn34b2provided by MGI
    Official Full Name
    claudin 34B2provided by MGI
    Primary source
    MGI:MGI:1920597
    See related
    Ensembl:ENSMUSG00000057402 AllianceGenome:MGI:1920597
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700042B14Rik
    Summary
    Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 9.0) See more
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    Genomic context

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    See Cldn34b2 in Genome Data Viewer
    Location:
    X F3; X 72.38 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (153907913..153930845, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (155124917..155147849, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene MAGE family member A5 Neighboring gene MAGE family member A1 Neighboring gene predicted gene, 25429 Neighboring gene predicted gene 4997 Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

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    Homology

    Clone Names

    • MGC117726

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    claudin 34B2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081671.2 → NP_001075140.1  claudin 34B2

      See identical proteins and their annotated locations for NP_001075140.1

      Status: VALIDATED

      Source sequence(s)
      AK006680, BC100353
      Consensus CDS
      CCDS53232.1
      UniProtKB/TrEMBL
      Q9D9N2
      Conserved Domains (1) summary
      cl21598
      Location:18 → 196
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    2. NM_028511.1 → NP_082787.1  claudin 34B2

      Status: VALIDATED

      Source sequence(s)
      AK006680, BX119986
      Consensus CDS
      CCDS53232.1
      UniProtKB/TrEMBL
      Q9D9N2
      Related
      ENSMUSP00000075967.4, ENSMUST00000076671.4
      Conserved Domains (1) summary
      cl21598
      Location:18 → 196
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      153907913..153930845 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247872.2 → XP_011246174.1  claudin 34B2 isoform X1

      See identical proteins and their annotated locations for XP_011246174.1

      UniProtKB/TrEMBL
      Q9D9N2
      Conserved Domains (1) summary
      cl21598
      Location:18 → 196
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
    Nucleotide Protein Strain
    Heading Accession and Version

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