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    Pramel61 PRAME like 60 [ Mus musculus (house mouse) ]

    Gene ID: 100041077, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pramel61provided by MGI
    Official Full Name
    PRAME like 60provided by MGI
    Primary source
    MGI:MGI:3703005
    See related
    Ensembl:ENSMUSG00000073723 AllianceGenome:MGI:3703005
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13102
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Pramel61 in Genome Data Viewer
    Location:
    4 E1; 4 77.98 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (143826450..143836671)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (144099880..144110101)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger, MYND domain containing 11 pseudogene Neighboring gene PRAME like 4 Neighboring gene STARR-seq mESC enhancer starr_11979 Neighboring gene STARR-seq mESC enhancer starr_11980 Neighboring gene oogenesin 3 Neighboring gene oogenesin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC164223, MGC164251

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables ubiquitin-like ligase-substrate adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100041077

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085419.1 → NP_001078888.1  uncharacterized protein LOC100041077

      See identical proteins and their annotated locations for NP_001078888.1

      Status: VALIDATED

      Source sequence(s)
      AL928630, AU020510, BC132592
      Consensus CDS
      CCDS57309.1
      UniProtKB/TrEMBL
      A2ASJ3, E0CXV0, F6SEH0, L7MU15, Q3ULC4
      Related
      ENSMUSP00000095408.4, ENSMUST00000097799.10
      Conserved Domains (1) summary
      sd00033
      Location:240 → 275
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      143826450..143836671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319879.1 → XP_017175368.1  uncharacterized protein LOC100041077 isoform X1

      UniProtKB/TrEMBL
      L7MU15
      Conserved Domains (1) summary
      sd00033
      Location:240 → 275
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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