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    Zfp1006 zinc finger protein 1006 [ Mus musculus (house mouse) ]

    Gene ID: 72139, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp1006provided by MGI
    Official Full Name
    zinc finger protein 1006provided by MGI
    Primary source
    MGI:MGI:1919389
    See related
    Ensembl:ENSMUSG00000071302 AllianceGenome:MGI:1919389
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610044O15Rik; 2610044O15Rik8
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to several human genes including ZNF117 (zinc finger protein 117); ZNF490 (zinc finger protein 490); and ZNF708 (zinc finger protein 708). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bladder adult (RPKM 2.6), CNS E11.5 (RPKM 1.9) and 21 other tissues See more
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    Genomic context

    See Zfp1006 in Genome Data Viewer
    Location:
    8 E2; 8
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (129942835..129960527, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (129216354..129234046, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 7A Neighboring gene predicted gene, 22545 Neighboring gene STARR-seq mESC enhancer starr_23110 Neighboring gene coiled-coil domain containing 7B Neighboring gene STARR-seq mESC enhancer starr_23111 Neighboring gene STARR-seq mESC enhancer starr_23112 Neighboring gene STARR-seq mESC enhancer starr_23113 Neighboring gene predicted gene, 22374 Neighboring gene STARR-seq mESC enhancer starr_23114 Neighboring gene STARR-seq mESC enhancer starr_23115 Neighboring gene peroxiredoxin pseudogene 2 Neighboring gene predicted gene, 32856

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of immune system process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC72139

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153780.3NP_722475.1  uncharacterized protein LOC72139

      See identical proteins and their annotated locations for NP_722475.1

      Status: VALIDATED

      Source sequence(s)
      AK138138
      Consensus CDS
      CCDS80947.1
      UniProtKB/TrEMBL
      E9Q1C8, Q8BG62
      Related
      ENSMUSP00000140736.2, ENSMUST00000190157.7
      Conserved Domains (1) summary
      pfam01352
      Location:441
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      129942835..129960527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)