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    Zfp949 zinc finger protein 949 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100233177, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp949provided by RGD
    Official Full Name
    zinc finger protein 949provided by RGD
    Primary source
    RGD:2302581
    See related
    EnsemblRapid:ENSRNOG00000043223 AllianceGenome:RGD:2302581
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 62.5), Liver (RPKM 59.1) and 9 other tissues See more
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    Genomic context

    See Zfp949 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (98402846..98427906)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (89522981..89548015)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (96356088..96380770)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein Neighboring gene small nucleolar RNA SNORD50 Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein, pseudogene 2 Neighboring gene tripartite motif-containing 43A Neighboring gene small nucleolar RNA SNORD50 Neighboring gene similar to RIKEN cDNA 4930579C12 gene Neighboring gene BCL2-related protein A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134531.1NP_001128003.1  zinc finger protein 717

      See identical proteins and their annotated locations for NP_001128003.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A6I1Z5, D3ZNQ5
      Related
      ENSRNOP00000034273.5, ENSRNOT00000032976.7
      Conserved Domains (6) summary
      smart00349
      Location:867
      KRAB; krueppel associated box
      COG5048
      Location:269599
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:438458
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:576598
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:847
      KRAB; KRAB box
      pfam13465
      Location:366389
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      98402846..98427906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)