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    Or8b12c olfactory receptor family 8 subfamily B member 12C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 405107, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or8b12cprovided by RGD
    Official Full Name
    olfactory receptor family 8 subfamily B member 12Cprovided by RGD
    Primary source
    RGD:1332681
    See related
    EnsemblRapid:ENSRNOG00000011563 AllianceGenome:RGD:1332681
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Olr1199
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or8b12c in Genome Data Viewer
    Location:
    8q22
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (45777500..45778435)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (37588759..37589694)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (40285637..40286572)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily B member 12D Neighboring gene olfactory receptor 1198 Neighboring gene U2 spliceosomal RNA Neighboring gene olfactory receptor family 8 subfamily B member 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor Olr1199
    Names
    olfactory receptor 1199
    olfactory receptor gene Olr1199

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001000819.2 → NP_001000819.2  olfactory receptor Olr1199

      Status: REVIEWED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6KRJ6, D3ZN02
      Related
      ENSRNOP00000015369.4, ENSRNOT00000015369.6
      Conserved Domains (1) summary
      cd15405
      Location:24 → 300
      7tmA_OR8B-like; olfactory receptor subfamily 8B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      45777500..45778435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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