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    Slc25a17 solute carrier family 25 member 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300083, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc25a17provided by RGD
    Official Full Name
    solute carrier family 25 member 17provided by RGD
    Primary source
    RGD:1311498
    See related
    EnsemblRapid:ENSRNOG00000076430 AllianceGenome:RGD:1311498
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable nucleobase-containing compound transmembrane transporter activity and protein-folding chaperone binding activity. Predicted to be involved in fatty acid beta-oxidation; fatty acid transport; and nucleotide transport. Predicted to be located in peroxisome. Predicted to be active in peroxisomal membrane. Orthologous to human SLC25A17 (solute carrier family 25 member 17). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 249.3), Kidney (RPKM 168.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc25a17 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (114724533..114767163, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (112844375..112887014, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (122539293..122581777, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479757 Neighboring gene uncharacterized LOC134479756 Neighboring gene transfer RNA serine (anticodon AGA) 50 Neighboring gene uncharacterized LOC120093696 Neighboring gene uncharacterized LOC134479943 Neighboring gene ST13, Hsp70 interacting protein Neighboring gene X-prolyl aminopeptidase 3 Neighboring gene DnaJ heat shock protein family (Hsp40) member B7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+. Agrimi G, et al. Biochem J, 2012 Apr 1. PMID 22185573
    2. The role of a microfinance program on HIV risk behavior among Haitian women. Rosenberg MS, et al. AIDS Behav, 2011 Jul. PMID 21153762
    3. Identification of human PMP34 as a peroxisomal ATP transporter. Visser WF, et al. Biochem Biophys Res Commun, 2002 Dec 6. PMID 12445829
    4. Topogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34. Honsho M, et al. J Biol Chem, 2001 Mar 23. PMID 11121399
    5. Multiple distinct targeting signals in integral peroxisomal membrane proteins. Jones JM, et al. J Cell Biol, 2001 Jun 11. PMID 11402059, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ADP transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables AMP transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ATP transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables FAD transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables FMN transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables NAD transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables coenzyme A transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in ADP transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in AMP transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ATP transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in FAD transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in NAD transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in coenzyme A transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid beta-oxidation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in nucleotide transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    peroxisomal membrane protein PMP34
    Names
    peroxisomal membrane protein, 34kDa
    peroxisomal membrane protein, 34kDa), member 17
    solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
    solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126269.1 → NP_001119741.1  peroxisomal membrane protein PMP34

      See identical proteins and their annotated locations for NP_001119741.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473950
      UniProtKB/TrEMBL
      A6HSZ1, B2GUY8
      Related
      ENSRNOP00000088770.2, ENSRNOT00000109011.2
      Conserved Domains (1) summary
      pfam00153
      Location:97 → 197
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      114724533..114767163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039078840.2 → XP_038934768.1  peroxisomal membrane protein PMP34 isoform X1

      UniProtKB/TrEMBL
      A6HSZ4
      Conserved Domains (1) summary
      pfam00153
      Location:10 → 95
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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