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    Tsc22d2 TSC22 domain family, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499624, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tsc22d2provided by RGD
    Official Full Name
    TSC22 domain family, member 2provided by RGD
    Primary source
    RGD:1593169
    See related
    EnsemblRapid:ENSRNOG00000038044 AllianceGenome:RGD:1593169
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of cell cycle. Predicted to act upstream of or within response to osmotic stress. Orthologous to human TSC22D2 (TSC22 domain family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 75.0), Kidney (RPKM 67.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tsc22d2 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (144796760..144847930)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (142646778..142697977)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (148607148..148659632)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L12, pseudogene 2 Neighboring gene U2 spliceosomal RNA Neighboring gene ribosomal protein S13, pseudogene 8 Neighboring gene stress-associated endoplasmic reticulum protein 1 Neighboring gene eukaryotic translation initiation factor 2A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    TSC22 domain family protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191960.1NP_001178889.1  TSC22 domain family protein 2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      D3ZDW3
      Related
      ENSRNOP00000062527.1, ENSRNOT00000015119.8
      Conserved Domains (1) summary
      pfam01166
      Location:682738
      TSC22; TSC-22/dip/bun family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      144796760..144847930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232386.4XP_006232448.1  TSC22 domain family protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006232448.1

      UniProtKB/TrEMBL
      A0A0G2K4L6, A6JVI5
      Related
      ENSRNOP00000073091.1, ENSRNOT00000088139.3
      Conserved Domains (1) summary
      pfam01166
      Location:658714
      TSC22; TSC-22/dip/bun family

    RNA

    1. XR_001836486.3 RNA Sequence