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    Zscan12 zinc finger and SCAN domain containing 12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266716, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zscan12provided by RGD
    Official Full Name
    zinc finger and SCAN domain containing 12provided by RGD
    Primary source
    RGD:628738
    See related
    AllianceGenome:RGD:628738
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp96
    Summary
    Predicted to be located in nucleus. Orthologous to human ZSCAN12 (zinc finger and SCAN domain containing 12). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 79.3), Heart (RPKM 72.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zscan12 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (47942976..47948930, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (43247250..43253206, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (45279171..45285069, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097923 Neighboring gene piggyBac transposable element derived 1 Neighboring gene zinc finger with KRAB and SCAN domains 3 Neighboring gene uncharacterized LOC120097820 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of a novel zinc finger protein (rZFP96) in the rat corpus luteum. Lareu RR, et al. Biochim Biophys Acta, 2005 Dec 30. PMID 16426687
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and SCAN domain-containing protein 12
    Names
    zinc finger protein 96

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430357.1 → NP_001417286.1  zinc finger and SCAN domain-containing protein 12

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72

    2. NM_001430358.1 → NP_001417287.1  zinc finger and SCAN domain-containing protein 12

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72

    3. NM_001430359.1 → NP_001417288.1  zinc finger and SCAN domain-containing protein 12

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      47942976..47948930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096200.2 → XP_038952128.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72
      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    2. XM_039096198.2 → XP_038952126.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    3. XM_039096202.2 → XP_038952130.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    4. XM_039096201.2 → XP_038952129.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72
      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    5. XM_039096199.2 → XP_038952127.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    6. XM_039096197.2 → XP_038952125.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72
      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    7. XM_039096196.2 → XP_038952124.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72
      Conserved Domains (4) summary
      smart00431
      Location:43 → 155
      SCAN; leucine rich region
      COG5048
      Location:209 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273 → 293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:457 → 479
      zf-C2H2; Zinc finger, C2H2 type

    8. XM_063276951.1 → XP_063133021.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72

    9. XM_063276950.1 → XP_063133020.1  zinc finger and SCAN domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K4Z9, A6KN72

    10. XM_039096204.1 → XP_038952132.1  zinc finger and SCAN domain-containing protein 12 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AD40, A6KN73
      Conserved Domains (4) summary
      COG5048
      Location:175 → 248
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:68 → 88
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:80 → 104
      zf-H2C2_2; Zinc-finger double domain
      cd20908
      Location:120 → 175
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153475.1: Suppressed sequence

      Description
      NM_153475.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

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