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    Idnk Idnk, gluconokinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498695, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Idnkprovided by RGD
    Official Full Name
    Idnk, gluconokinaseprovided by RGD
    Primary source
    RGD:1564546
    See related
    EnsemblRapid:ENSRNOG00000019519 AllianceGenome:RGD:1564546
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Orthologous to human IDNK (IDNK gluconokinase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 30.6), Liver (RPKM 18.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Idnk in Genome Data Viewer
    Location:
    17p14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (6489397..6496520, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (6483575..6490780, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (6885323..6892603, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene ubiquilin 1 Neighboring gene uncharacterized LOC134482668 Neighboring gene heterogeneous nuclear ribonucleoprotein A0

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC125086

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gluconokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-gluconate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    probable gluconokinase
    Names
    gluconate kinase
    idnK, gluconokinase homolog
    NP_001032439.1
    XP_006253625.1
    XP_006253626.1
    XP_038951917.1
    XP_038951918.2
    XP_063132752.1
    XP_063132754.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037362.1 → NP_001032439.1  probable gluconokinase

      See identical proteins and their annotated locations for NP_001032439.1

      Status: PROVISIONAL

      Source sequence(s)
      BC107923
      UniProtKB/Swiss-Prot
      Q32PY9
      UniProtKB/TrEMBL
      A0A8I5Y4K0, A6KAL2
      Related
      ENSRNOP00000082724.1, ENSRNOT00000116956.2
      Conserved Domains (2) summary
      COG0703
      Location:10 → 185
      AroK; Shikimate kinase [Amino acid transport and metabolism]
      COG3265
      Location:10 → 185
      GntK; Gluconate kinase [Carbohydrate transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      6489397..6496520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095990.2 → XP_038951918.2  probable gluconokinase isoform X4

    2. XM_006253563.5 → XP_006253625.1  probable gluconokinase isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y4K0, A0A8I6AFF0
      Related
      ENSRNOP00000091550.1, ENSRNOT00000113237.2
      Conserved Domains (1) summary
      cl17190
      Location:38 → 196
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    3. XM_006253564.5 → XP_006253626.1  probable gluconokinase isoform X6

      UniProtKB/TrEMBL
      A0A8L2QEZ2
      Related
      ENSRNOP00000026407.5, ENSRNOT00000026407.9
      Conserved Domains (1) summary
      cl17190
      Location:6 → 55
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    4. XM_039095989.2 → XP_038951917.1  probable gluconokinase isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y4K0
      Conserved Domains (1) summary
      cl17190
      Location:1 → 139
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    5. XM_063276682.1 → XP_063132752.1  probable gluconokinase isoform X3

      UniProtKB/TrEMBL
      A6KAL3

    6. XM_063276684.1 → XP_063132754.1  probable gluconokinase isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32PY9.1 GenPept UniProtKB/Swiss-Prot:Q32PY9

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