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    Gosr1 golgi SNAP receptor complex member 1 [ Mus musculus (house mouse) ]

    Gene ID: 53334, updated on 27-Nov-2024

    Summary

    Official Symbol
    Gosr1provided by MGI
    Official Full Name
    golgi SNAP receptor complex member 1provided by MGI
    Primary source
    MGI:MGI:1858260
    See related
    Ensembl:ENSMUSG00000010392 AllianceGenome:MGI:1858260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GS28; GOSRI; GOS-28
    Summary
    Predicted to enable SNAP receptor activity. Predicted to be involved in Golgi vesicle transport; retrograde transport, endosome to Golgi; and vesicle fusion. Located in Golgi membrane. Orthologous to human GOSR1 (golgi SNAP receptor complex member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 9.6), placenta adult (RPKM 9.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gosr1 in Genome Data Viewer
    Location:
    11 B5; 11 46.02 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (76617428..76654404, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (76726602..76763578, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix family, member a9 Neighboring gene trafficking regulator of GLUT4 (SLC2A4) 1 Neighboring gene STARR-positive B cell enhancer ABC_E9829 Neighboring gene STARR-positive B cell enhancer ABC_E3977 Neighboring gene carboxypeptidase D Neighboring gene STARR-seq mESC enhancer starr_30045 Neighboring gene predicted gene, 53688 Neighboring gene predicted gene, 40200

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SNAP receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inter-Golgi cisterna vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi medial cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cis-Golgi network IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Golgi SNAP receptor complex member 1
    Names
    28 kDa Golgi SNARE protein
    28 kDa cis-Golgi SNARE p28
    Cis-Golgi SNARE

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356321.1NP_001343250.1  Golgi SNAP receptor complex member 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AK133836, AK147799, AK161386, BQ032729, CB522161
      UniProtKB/TrEMBL
      Q80UU0
      Conserved Domains (1) summary
      cd15864
      Location:158223
      SNARE_GS28; SNARE motif of GS28
    2. NM_016810.4NP_058090.2  Golgi SNAP receptor complex member 1 isoform 1

      See identical proteins and their annotated locations for NP_058090.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK133836, AK147799, AK161386, BQ032729
      Consensus CDS
      CCDS25070.1
      UniProtKB/Swiss-Prot
      O88630, Q91VU9
      UniProtKB/TrEMBL
      Q80UU0
      Related
      ENSMUSP00000010536.9, ENSMUST00000010536.9
      Conserved Domains (1) summary
      cd15864
      Location:160225
      SNARE_GS28; SNARE motif of GS28

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      76617428..76654404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)