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    Virma vir like m6A methyltransferase associated [ Mus musculus (house mouse) ]

    Gene ID: 66185, updated on 9-Dec-2024

    Summary

    Official Symbol
    Virmaprovided by MGI
    Official Full Name
    vir like m6A methyltransferase associatedprovided by MGI
    Primary source
    MGI:MGI:1913435
    See related
    Ensembl:ENSMUSG00000040720 AllianceGenome:MGI:1913435
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kiaa1429; mKIAA1429; 1110037F02Rik; 4930422M05Rik
    Summary
    Predicted to be involved in mRNA modification and mRNA processing. Located in cytoplasm and nucleus. Part of RNA N6-methyladenosine methyltransferase complex. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human VIRMA (vir like m6A methyltransferase associated). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 9.4), CNS E11.5 (RPKM 9.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Virma in Genome Data Viewer
    Location:
    4 A1; 4 5.11 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (11485958..11551143)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (11485958..11551143)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09598 Neighboring gene predicted gene, 35631 Neighboring gene predicted gene 11821 Neighboring gene STARR-positive B cell enhancer ABC_E4613 Neighboring gene STARR-seq mESC enhancer starr_09599 Neighboring gene STARR-positive B cell enhancer ABC_E338 Neighboring gene STARR-seq mESC enhancer starr_09600 Neighboring gene STARR-positive B cell enhancer ABC_E4614 Neighboring gene predicted gene, 53245 Neighboring gene predicted gene, 35693 Neighboring gene RAD54 homolog B (S. cerevisiae) Neighboring gene fibrinogen silencer binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4)  1 citation
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of RNA N6-methyladenosine methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA N6-methyladenosine methyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of RNA N6-methyladenosine methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA N6-methyladenosine methyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081183.1NP_001074652.1  protein virilizer homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL732538, AL772170
      Consensus CDS
      CCDS38693.1
      UniProtKB/TrEMBL
      E9PZY8
      Related
      ENSMUSP00000103943.3, ENSMUST00000108307.3
      Conserved Domains (2) summary
      pfam15502
      Location:17521857
      MPLKIP; M-phase-specific PLK1-interacting protein
      pfam15912
      Location:5236
      VIR_N; Virilizer, N-terminal
    2. NM_001347055.1NP_001333984.1  protein virilizer homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AL732538, AL772170
      Consensus CDS
      CCDS84705.1
      UniProtKB/Swiss-Prot
      A2AIV1, A2AIV2, Q3TDQ3, Q3TRR9, Q3U1Z2, Q80TD6, Q8C758, Q8K151, Q9CSI3
      Related
      ENSMUSP00000058078.7, ENSMUST00000059914.13

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      11485958..11551143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)