U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Dab1 disabled 1 [ Mus musculus (house mouse) ]

    Gene ID: 13131, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dab1provided by MGI
    Official Full Name
    disabled 1provided by MGI
    Primary source
    MGI:MGI:108554
    See related
    Ensembl:ENSMUSG00000028519 AllianceGenome:MGI:108554
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    scm; scr; yot; mDab1; scrambler; C630028C02Rik
    Summary
    Enables signaling adaptor activity. Involved in nervous system development; reelin-mediated signaling pathway; and regulation of synapse maturation. Acts upstream of or within several processes, including adult walking behavior; negative regulation of neurogenesis; and nervous system development. Located in perinuclear region of cytoplasm. Is active in cytoplasm and glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 14.1), whole brain E14.5 (RPKM 10.9) and 11 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dab1 in Genome Data Viewer
    Location:
    4 C6; 4 47.79 cM
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (103476425..104602041)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (103619500..104744844)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene actin, gamma, cytoplasmic 1 pseudogene Neighboring gene predicted gene, 25877 Neighboring gene predicted gene, 36604 Neighboring gene STARR-seq mESC enhancer starr_10943 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 36661 Neighboring gene STARR-seq mESC enhancer starr_10944 Neighboring gene STARR-seq mESC enhancer starr_10945 Neighboring gene STARR-seq mESC enhancer starr_10949 Neighboring gene STARR-seq mESC enhancer starr_10950 Neighboring gene complement component 8, beta polypeptide Neighboring gene complement component 8, alpha polypeptide Neighboring gene FYN binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH2 domain binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables phosphatidylinositol 3-kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phospholipid binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within adult walking behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of astrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of axonogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of cell surface receptor signaling pathway via JAK-STAT IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in central nervous system development TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within cerebellum structural organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cerebral cortex cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cerebral cortex radially oriented cell migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within cerebral cortex radially oriented cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cerebral cortex radially oriented cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cerebral cortex radially oriented cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within dendrite development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within hippocampus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in lateral motor column neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within motor neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of astrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of axonogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of receptor signaling pathway via JAK-STAT IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nervous system development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within neuron migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein kinase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within radial glia guided migration of Purkinje cell IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within radial glia guided migration of Purkinje cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in radial glia guided migration of Purkinje cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within radial glia-guided pyramidal neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in reelin-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of synapse maturation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of synapse maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within small GTPase-mediated signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ventral spinal cord development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    located_in brush border ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    disabled homolog 1
    Names
    yotari

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001369046.1NP_001355975.1  disabled homolog 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variants 2 and 5, encodes isoform 2.
      Source sequence(s)
      AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
      Consensus CDS
      CCDS18413.1
      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      UniProtKB/TrEMBL
      B2RRQ8
      Conserved Domains (2) summary
      PRK07764
      Location:255436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    2. NM_001369047.1NP_001355976.1  disabled homolog 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 2 and 4, encodes isoform 2.
      Source sequence(s)
      AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
      Consensus CDS
      CCDS18413.1
      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      UniProtKB/TrEMBL
      B2RRQ8
      Conserved Domains (2) summary
      PRK07764
      Location:255436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    3. NM_001369048.1NP_001355977.1  disabled homolog 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
      Consensus CDS
      CCDS89790.1
      Related
      ENSMUSP00000102440.2, ENSMUST00000106827.8
      Conserved Domains (1) summary
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    4. NM_001369049.1NP_001355978.1  disabled homolog 1 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) encodes the longest isoform (4).
      Source sequence(s)
      AL626762, AL627134, AL645483, AL645666, AL669938, AL772211
      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    5. NM_010014.3NP_034144.1  disabled homolog 1 isoform 1

      See identical proteins and their annotated locations for NP_034144.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks several exons and includes an alternate 3' terminal exon, compared to variant 2. It encodes isoform 1 which is shorter and has a distinct C-terminus, compared to isoform 2.
      Source sequence(s)
      BE947086, BY264959, Y08381
      UniProtKB/Swiss-Prot
      P97318
      Related
      ENSMUSP00000102439.2, ENSMUST00000106826.8
      Conserved Domains (1) summary
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    6. NM_177259.4NP_796233.2  disabled homolog 1 isoform 2

      See identical proteins and their annotated locations for NP_796233.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 4 and 5, encodes isoform 2.
      Source sequence(s)
      AK045616, BC138538, BE945099, BY264959, Y08379
      Consensus CDS
      CCDS18413.1
      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      UniProtKB/TrEMBL
      B2RRQ8
      Related
      ENSMUSP00000102443.3, ENSMUST00000106830.9
      Conserved Domains (2) summary
      PRK07764
      Location:255436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain

    RNA

    1. NR_104385.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL627134, AL645483, AL669938

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      103476425..104602041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163642.1XP_036019535.1  disabled homolog 1 isoform X5

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    2. XM_036163645.1XP_036019538.1  disabled homolog 1 isoform X15

      Conserved Domains (1) summary
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    3. XM_006502725.5XP_006502788.1  disabled homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006502788.1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    4. XM_036163638.1XP_036019531.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    5. XM_036163640.1XP_036019533.1  disabled homolog 1 isoform X4

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      UniProtKB/TrEMBL
      B2RRQ8
      Conserved Domains (2) summary
      PRK07764
      Location:255436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    6. XM_036163635.1XP_036019528.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    7. XM_011240426.3XP_011238728.1  disabled homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_011238728.1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    8. XM_036163636.1XP_036019529.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    9. XM_030253166.2XP_030109026.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    10. XM_036163637.1XP_036019530.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    11. XM_036163641.1XP_036019534.1  disabled homolog 1 isoform X5

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    12. XM_036163633.1XP_036019526.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    13. XM_036163632.1XP_036019525.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    14. XM_030253165.2XP_030109025.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    15. XM_017319948.2XP_017175437.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    16. XM_030253172.2XP_030109032.1  disabled homolog 1 isoform X5

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    17. XM_006502727.5XP_006502790.1  disabled homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006502790.1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    18. XM_030253170.2XP_030109030.1  disabled homolog 1 isoform X4

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      UniProtKB/TrEMBL
      B2RRQ8
      Conserved Domains (2) summary
      PRK07764
      Location:255436
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    19. XM_030253175.2XP_030109035.1  disabled homolog 1 isoform X8

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PHA03247
      Location:254434
      PHA03247; large tegument protein UL36; Provisional
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    20. XM_030253182.2XP_030109042.1  disabled homolog 1 isoform X15

      Conserved Domains (1) summary
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    21. XM_036163643.1XP_036019536.1  disabled homolog 1 isoform X12

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:220401
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    22. XM_036163644.1XP_036019537.1  disabled homolog 1 isoform X14

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:220401
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    23. XM_030253180.2XP_030109040.1  disabled homolog 1 isoform X15

      Conserved Domains (1) summary
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    24. XM_030253169.2XP_030109029.1  disabled homolog 1 isoform X3

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PHA03247
      Location:287467
      PHA03247; large tegument protein UL36; Provisional
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    25. XM_030253177.2XP_030109037.1  disabled homolog 1 isoform X10

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    26. XM_006502726.2XP_006502789.1  disabled homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006502789.1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    27. XM_030253174.1XP_030109034.1  disabled homolog 1 isoform X7

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:251432
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    28. XM_030253167.2XP_030109027.1  disabled homolog 1 isoform X2

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:286467
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    29. XM_030253173.2XP_030109033.1  disabled homolog 1 isoform X6

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    30. XM_030253171.1XP_030109031.1  disabled homolog 1 isoform X5

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:253434
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    31. XM_017319950.3XP_017175439.1  disabled homolog 1 isoform X8

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PHA03247
      Location:254434
      PHA03247; large tegument protein UL36; Provisional
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    32. XM_030253176.2XP_030109036.1  disabled homolog 1 isoform X9

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PHA03247
      Location:252432
      PHA03247; large tegument protein UL36; Provisional
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    33. XM_030253178.1XP_030109038.1  disabled homolog 1 isoform X12

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:220401
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    34. XM_030253179.2XP_030109039.1  disabled homolog 1 isoform X13

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:218399
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    35. XM_036163639.1XP_036019532.1  disabled homolog 1 isoform X1

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:288469
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01215
      Location:25174
      PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    36. XM_006502735.3XP_006502798.1  disabled homolog 1 isoform X11

      UniProtKB/Swiss-Prot
      A2A963, A2A964, A2A965, A2A966, A2A967, A2A970, P97316, P97317, P97318, Q9DAP9
      Conserved Domains (2) summary
      PRK07764
      Location:224405
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cl17171
      Location:1110
      PH-like; Pleckstrin homology-like domain