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    Serpinb9g serine (or cysteine) peptidase inhibitor, clade B, member 9g [ Mus musculus (house mouse) ]

    Gene ID: 93806, updated on 9-Dec-2024

    Summary

    Official Symbol
    Serpinb9gprovided by MGI
    Official Full Name
    serine (or cysteine) peptidase inhibitor, clade B, member 9gprovided by MGI
    Primary source
    MGI:MGI:1919260
    See related
    Ensembl:ENSMUSG00000057726 AllianceGenome:MGI:1919260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NK21B; 1600002F03Rik
    Summary
    Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protease binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of endopeptidase activity; and protection from natural killer cell mediated cytotoxicity. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in cytoplasm and extracellular space. Orthologous to human SERPINB9 (serpin family B member 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 103.2) See more
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    Genomic context

    See Serpinb9g in Genome Data Viewer
    Location:
    13 A3.3; 13 13.9 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (33668773..33679985)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (33484790..33496002)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 9h Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 9 pseudogene Neighboring gene STARR-seq mESC enhancer starr_34119 Neighboring gene STARR-seq mESC enhancer starr_34120 Neighboring gene STARR-seq mESC enhancer starr_34121 Neighboring gene serpin B9-like Neighboring gene predicted gene 11386

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    enables protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables serine-type endopeptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in immune response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protection from natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    serine (or cysteine) proteinase inhibitor, clade B, member 9g
    Names
    ovalbumin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011455.3NP_035585.2  serine (or cysteine) proteinase inhibitor, clade B, member 9g

      See identical proteins and their annotated locations for NP_035585.2

      Status: VALIDATED

      Source sequence(s)
      AK005394, BC064758, BC064759
      Consensus CDS
      CCDS26438.1
      UniProtKB/TrEMBL
      Q8VHQ1, Q9DAZ7
      Related
      ENSMUSP00000080597.3, ENSMUST00000081927.4
      Conserved Domains (1) summary
      cl00137
      Location:4377
      SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      33668773..33679985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)