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    Cd200r4 CD200 receptor 4 [ Mus musculus (house mouse) ]

    Gene ID: 239849, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cd200r4provided by MGI
    Official Full Name
    CD200 receptor 4provided by MGI
    Primary source
    MGI:MGI:3036289
    See related
    Ensembl:ENSMUSG00000062082 AllianceGenome:MGI:3036289
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MCD200RLa; F630107N04Rik
    Summary
    Enables signaling receptor activity. Predicted to be involved in regulation of neuroinflammatory response. Located in external side of plasma membrane. Is expressed in ductus deferens; epididymis; ileum; and tongue. Orthologous to several human genes including CD200R1 (CD200 receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Cd200r4 in Genome Data Viewer
    Location:
    16 B4; 16 29.12 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (44632036..44659497)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (44811650..44839150)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein pseudogene Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene Cd200 receptor 2 Neighboring gene predicted gene, 53957 Neighboring gene Cd200 receptor 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding PubMed 
    enables signaling receptor activity  
    enables signaling receptor activity PubMed 
    Component Evidence Code Pubs
    located_in cell surface  
    is_active_in external side of plasma membrane  
    located_in external side of plasma membrane PubMed 
    located_in plasma membrane  

    General protein information

    Preferred Names
    cell surface glycoprotein CD200 receptor 4
    Names
    CD200 cell surface glycoprotein receptor
    CD200 cell surface glycoprotein receptor-like 4
    CD200 cell surface glycoprotein receptor-like a
    CD200 receptor-like 4
    CD200RLa
    cell surface glycoprotein OX2 receptor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207244.3NP_997127.1  cell surface glycoprotein CD200 receptor 4 precursor

      See identical proteins and their annotated locations for NP_997127.1

      Status: VALIDATED

      Source sequence(s)
      AC122217
      Consensus CDS
      CCDS37346.1
      UniProtKB/Swiss-Prot
      Q6XJV4
      Related
      ENSMUSP00000135299.2, ENSMUST00000176819.8
      Conserved Domains (1) summary
      cl11960
      Location:42147
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      44632036..44659497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245895.4XP_011244197.1  cell surface glycoprotein CD200 receptor 4 isoform X2

      See identical proteins and their annotated locations for XP_011244197.1

      UniProtKB/TrEMBL
      H3BJX3
      Related
      ENSMUSP00000135162.3, ENSMUST00000176321.8
      Conserved Domains (1) summary
      cl11960
      Location:116184
      Ig; Immunoglobulin domain
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