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    Pced1b PC-esterase domain containing 1B [ Mus musculus (house mouse) ]

    Gene ID: 239647, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Pced1bprovided by MGI
    Official Full Name
    PC-esterase domain containing 1Bprovided by MGI
    Primary source
    MGI:MGI:2446270
    See related
    Ensembl:ENSMUSG00000044250 AllianceGenome:MGI:2446270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam113b
    Summary
    Orthologous to human PCED1B (PC-esterase domain containing 1B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in spleen adult (RPKM 7.5), ovary adult (RPKM 4.7) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Pced1b in Genome Data Viewer
    Location:
    15 F1; 15 52.91 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (97143563..97283574)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (97246973..97385693)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39614 Neighboring gene predicted gene, 32885 Neighboring gene predicted gene, 33149 Neighboring gene STARR-seq mESC enhancer starr_39615 Neighboring gene predicted gene, 33253 Neighboring gene predicted gene, 33205 Neighboring gene STARR-positive B cell enhancer mm9_chr15:97089728-97090029 Neighboring gene predicted gene, 57814 Neighboring gene adhesion molecule with Ig like domain 2 Neighboring gene STARR-seq mESC enhancer starr_39616 Neighboring gene high mobility group box 2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8610 Neighboring gene STARR-positive B cell enhancer ABC_E9920 Neighboring gene STARR-positive B cell enhancer ABC_E7414 Neighboring gene predicted gene, 33325 Neighboring gene STARR-positive B cell enhancer ABC_E1484 Neighboring gene STARR-seq mESC enhancer starr_39625 Neighboring gene STARR-seq mESC enhancer starr_39629 Neighboring gene predicted gene, 41393 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:97289192-97289405 Neighboring gene STARR-seq mESC enhancer starr_39631 Neighboring gene STARR-seq mESC enhancer starr_39632 Neighboring gene STARR-seq mESC enhancer starr_39633 Neighboring gene STARR-seq mESC enhancer starr_39634 Neighboring gene predicted gene, 41394

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC47262

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    PC-esterase domain-containing protein 1B
    Names
    family with sequence similarity 113, member B
    protein FAM113B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001416134.1 → NP_001403063.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    2. NM_001416135.1 → NP_001403064.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Related
      ENSMUSP00000154814.2, ENSMUST00000228521.2

    3. NM_001416136.1 → NP_001403065.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    4. NM_001416137.1 → NP_001403066.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    5. NM_001416138.1 → NP_001403067.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    6. NM_001416139.1 → NP_001403068.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    7. NM_001416140.1 → NP_001403069.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    8. NM_001416141.1 → NP_001403070.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    9. NM_001416142.1 → NP_001403071.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    10. NM_001416143.1 → NP_001403072.1  PC-esterase domain-containing protein 1B

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1

    11. NM_172293.5 → NP_758497.1  PC-esterase domain-containing protein 1B

      See identical proteins and their annotated locations for NP_758497.1

      Status: VALIDATED

      Source sequence(s)
      AC102914, AC161194
      Consensus CDS
      CCDS27781.1
      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Related
      ENSMUSP00000055485.7, ENSMUST00000059433.8
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      97143563..97283574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245624.2 → XP_011243926.1  PC-esterase domain-containing protein 1B isoform X1

      See identical proteins and their annotated locations for XP_011243926.1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    2. XM_011245626.4 → XP_011243928.1  PC-esterase domain-containing protein 1B isoform X1

      See identical proteins and their annotated locations for XP_011243928.1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    3. XM_036159404.1 → XP_036015297.1  PC-esterase domain-containing protein 1B isoform X1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    4. XM_011245625.3 → XP_011243927.1  PC-esterase domain-containing protein 1B isoform X1

      See identical proteins and their annotated locations for XP_011243927.1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    5. XM_006520967.5 → XP_006521030.1  PC-esterase domain-containing protein 1B isoform X1

      See identical proteins and their annotated locations for XP_006521030.1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    6. XM_006520968.5 → XP_006521031.1  PC-esterase domain-containing protein 1B isoform X1

      See identical proteins and their annotated locations for XP_006521031.1

      UniProtKB/Swiss-Prot
      Q5RK34, Q8BGX1
      Conserved Domains (1) summary
      cl01053
      Location:17 → 253
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BGX1.1 GenPept UniProtKB/Swiss-Prot:Q8BGX1

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