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    Zfp791 zinc finger protein 791 [ Mus musculus (house mouse) ]

    Gene ID: 244556, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp791provided by MGI
    Official Full Name
    zinc finger protein 791provided by MGI
    Primary source
    MGI:MGI:3648473
    See related
    Ensembl:ENSMUSG00000074194 AllianceGenome:MGI:3648473
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG244556
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF791 (zinc finger protein 791). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E18 (RPKM 1.9), bladder adult (RPKM 1.1) and 22 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp791 in Genome Data Viewer
    Location:
    8 C3; 8 41.55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (85833797..85849724, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (85107168..85123095, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 83 opposite strand Neighboring gene mannosidase 2, alpha B1 Neighboring gene predicted gene, 42031 Neighboring gene STARR-seq mESC enhancer starr_22151 Neighboring gene CDC28 protein kinase 1b, retrogene Neighboring gene predicted gene, 33296 Neighboring gene zinc finger protein 46 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Hematologic characterization and chromosomal localization of the novel dominantly inherited mouse hemolytic anemia, neonatal anemia (Nan). White RA, et al. Blood Cells Mol Dis, 2009 Sep-Oct. PMID 19409822
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Homology

    Clone Names

    • MGC117728

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 791

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037745.2 → NP_001032834.1  zinc finger protein 791 isoform 1

      See identical proteins and their annotated locations for NP_001032834.1

      Status: VALIDATED

      Source sequence(s)
      AC163703, BC100354
      Consensus CDS
      CCDS40419.1
      UniProtKB/TrEMBL
      Q497V9
      Related
      ENSMUSP00000147335.2, ENSMUST00000211109.2
      Conserved Domains (4) summary
      COG5048
      Location:95 → 468
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:445 → 528
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 43
      KRAB; KRAB box

    2. NM_001357366.1 → NP_001344295.1  zinc finger protein 791 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC163703
      Conserved Domains (4) summary
      COG5048
      Location:94 → 467
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:444 → 527
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:422 → 442
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 43
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      85833797..85849724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243545.2 → XP_030099405.1  zinc finger protein 791 isoform X1

      UniProtKB/TrEMBL
      Q497V9
      Related
      ENSMUSP00000096150.4, ENSMUST00000098550.4
      Conserved Domains (4) summary
      COG5048
      Location:95 → 468
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:445 → 528
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 43
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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