Vwa5b1 von Willebrand factor A domain containing 5B1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vwa5b1provided by MGI
Official Full Name: von Willebrand factor A domain containing 5B1provided by MGI
Primary source: MGI:MGI:1922968
See related: Ensembl:ENSMUSG00000028753 AllianceGenome:MGI:1922968
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4931403E03Rik
Summary: Predicted to be located in extracellular region. Orthologous to human VWA5B1 (von Willebrand factor A domain containing 5B1). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in testis adult (RPKM 7.2) and CNS E18 (RPKM 0.4) See more
Orthologs: human all
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Genomic context

Location:: 4 D3; 4 70.43 cM

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (138291540..138363303, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (138564229..138635992, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)
Targeted (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D4Mit170 (e-PCR), detects polymorphism
- UniSTS:129950

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: von Willebrand factor A domain-containing protein 5B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029401.1 → NP_083677.1 von Willebrand factor A domain-containing protein 5B1 precursor

Status: PROVISIONAL

Source sequence(s)

BC132477

Consensus CDS

CCDS51336.1

UniProtKB/Swiss-Prot

A9Z1V5, Q6PFX4, Q9CUE8

UniProtKB/TrEMBL

B1AZ81

Related

ENSMUSP00000030533.6, ENSMUST00000030533.12

Conserved Domains (2) summary

cd01461
Location:351 → 519

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:16 → 561

marine_srt_targ; marine proteobacterial sortase target protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000070.7 Reference GRCm39 C57BL/6J

Range

138291540..138363303 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006539245.4 → XP_006539308.1 von Willebrand factor A domain-containing protein 5B1 isoform X3

Conserved Domains (2) summary

cd01461
Location:365 → 533

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:30 → 575

marine_srt_targ; marine proteobacterial sortase target protein
XM_006539241.4 → XP_006539304.1 von Willebrand factor A domain-containing protein 5B1 isoform X1

Conserved Domains (2) summary

cd01461
Location:365 → 533

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:30 → 575

marine_srt_targ; marine proteobacterial sortase target protein
XM_036164524.1 → XP_036020417.1 von Willebrand factor A domain-containing protein 5B1 isoform X4

Conserved Domains (2) summary

cd01461
Location:365 → 533

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

cl02699
Location:16 → 93

VIT; Vault protein inter-alpha-trypsin domain
XM_017320433.2 → XP_017175922.1 von Willebrand factor A domain-containing protein 5B1 isoform X2

UniProtKB/Swiss-Prot

A9Z1V5, Q6PFX4, Q9CUE8

UniProtKB/TrEMBL

B1AZ81

Conserved Domains (2) summary

cd01461
Location:351 → 519

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:16 → 561

marine_srt_targ; marine proteobacterial sortase target protein
XM_006539243.4 → XP_006539306.1 von Willebrand factor A domain-containing protein 5B1 isoform X2

UniProtKB/Swiss-Prot

A9Z1V5, Q6PFX4, Q9CUE8

UniProtKB/TrEMBL

B1AZ81

Conserved Domains (2) summary

cd01461
Location:351 → 519

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:16 → 561

marine_srt_targ; marine proteobacterial sortase target protein
XM_006539244.2 → XP_006539307.1 von Willebrand factor A domain-containing protein 5B1 isoform X2

UniProtKB/Swiss-Prot

A9Z1V5, Q6PFX4, Q9CUE8

UniProtKB/TrEMBL

B1AZ81

Conserved Domains (2) summary

cd01461
Location:351 → 519

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:16 → 561

marine_srt_targ; marine proteobacterial sortase target protein
XM_011250349.1 → XP_011248651.1 von Willebrand factor A domain-containing protein 5B1 isoform X2

UniProtKB/Swiss-Prot

A9Z1V5, Q6PFX4, Q9CUE8

UniProtKB/TrEMBL

B1AZ81

Conserved Domains (2) summary

cd01461
Location:351 → 519

vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...

TIGR03788
Location:16 → 561

marine_srt_targ; marine proteobacterial sortase target protein