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    Mfsd4b1 major facilitator superfamily domain containing 4B1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499462, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Mfsd4b1provided by RGD
    Official Full Name
    major facilitator superfamily domain containing 4B1provided by RGD
    Primary source
    RGD:1559971
    See related
    EnsemblRapid:ENSRNOG00000024543 AllianceGenome:RGD:1559971
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mfsd4b; RGD1559971
    Summary
    Predicted to enable D-glucose transmembrane transporter activity. Predicted to be involved in hexose transmembrane transport. Predicted to be located in membrane. Orthologous to human MFSD4B (major facilitator superfamily domain containing 4B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 157.0), Muscle (RPKM 41.1) and 9 other tissues See more
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    Genomic context

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    See Mfsd4b1 in Genome Data Viewer
    Location:
    20q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (44878985..44888435, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (43324419..43333869, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (44996864..45005155, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene U6atac minor spliceosomal RNA Neighboring gene REV3 like, DNA directed polymerase zeta catalytic subunit Neighboring gene peptidylprolyl isomerase G, pseudogene 2 Neighboring gene uncharacterized LOC120098823 Neighboring gene major facilitator superfamily domain containing 4B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in hexose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    major facilitator superfamily domain containing 4B
    Names
    sodium-dependent glucose transporter 1C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402082.1 → NP_001389011.1  major facilitator superfamily domain containing 4B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A6KIH2, F1LTM4
      Related
      ENSRNOP00000036588.6, ENSRNOT00000035047.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      44878985..44888435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099152.2 → XP_038955080.1  major facilitator superfamily domain containing 4B isoform X1

      Conserved Domains (1) summary
      cl28910
      Location:1 → 359
      MFS; Major Facilitator Superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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