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    Ralyl RALY RNA binding protein-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294883, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ralylprovided by RGD
    Official Full Name
    RALY RNA binding protein-likeprovided by RGD
    Primary source
    RGD:1305844
    See related
    EnsemblRapid:ENSRNOG00000011400 AllianceGenome:RGD:1305844
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305844
    Summary
    Predicted to enable RNA binding activity and identical protein binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human RALYL (RALY RNA binding protein like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 86.3), Adrenal (RPKM 13.9) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ralyl in Genome Data Viewer
    Location:
    2q23
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (89390212..90181681, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (87482747..88274329, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (89039990..89842784, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 like 1 Neighboring gene U1 small nuclear ribonucleoprotein C-like Neighboring gene eukaryotic translation initiation factor 1 pseudogene Neighboring gene large ribosomal subunit protein eL34-like Neighboring gene aldolase, fructose-bisphosphate A, pseudogene 5 Neighboring gene GTPase activating protein testicular GAP1 like 1 Neighboring gene N(alpha)-acetyltransferase 11, NatA catalytic subunit, pseudogene 9 Neighboring gene thioredoxin-like 4A like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    2. Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding Raly-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024978.2 → NP_001020149.2  RNA-binding Raly-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      Q569A4
      Related
      ENSRNOP00000077377.2, ENSRNOT00000096427.2

    2. NM_001393770.1 → NP_001380699.1  RNA-binding Raly-like protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      F7F855, Q569A4
      Related
      ENSRNOP00000015195.7, ENSRNOT00000015195.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      89390212..90181681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590724.2 → XP_017446213.1  RNA-binding Raly-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8I6AIC1, A6IH25
      Related
      ENSRNOP00000094728.1, ENSRNOT00000100768.2
      Conserved Domains (2) summary
      pfam10779
      Location:201 → 246
      XhlA; Haemolysin XhlA
      cl17169
      Location:15 → 97
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_063281532.1 → XP_063137602.1  RNA-binding Raly-like protein isoform X5

    3. XM_017590727.3 → XP_017446216.1  RNA-binding Raly-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8I6AIC1, A6IH25
      Conserved Domains (2) summary
      pfam10779
      Location:201 → 246
      XhlA; Haemolysin XhlA
      cl17169
      Location:15 → 97
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. XM_039101954.2 → XP_038957882.1  RNA-binding Raly-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8I6AIC1, A6IH25
      Conserved Domains (2) summary
      pfam10779
      Location:201 → 246
      XhlA; Haemolysin XhlA
      cl17169
      Location:15 → 97
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_017590722.3 → XP_017446211.1  RNA-binding Raly-like protein isoform X1

      UniProtKB/TrEMBL
      D3ZW44
      Related
      ENSRNOP00000063407.4, ENSRNOT00000068507.5

    6. XM_039101952.2 → XP_038957880.1  RNA-binding Raly-like protein isoform X2

      Conserved Domains (2) summary
      COG3883
      Location:221 → 271
      CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
      cl17169
      Location:40 → 122
      RRM_SF; RNA recognition motif (RRM) superfamily

    7. XM_017590726.3 → XP_017446215.1  RNA-binding Raly-like protein isoform X4

    8. XM_063281534.1 → XP_063137604.1  RNA-binding Raly-like protein isoform X7

    9. XM_008760853.4 → XP_008759075.2  RNA-binding Raly-like protein isoform X6

      UniProtKB/TrEMBL
      A6IH26
      Related
      ENSRNOP00000107066.1, ENSRNOT00000158783.1
      Conserved Domains (1) summary
      pfam10779
      Location:128 → 173
      XhlA; Haemolysin XhlA

    10. XM_063281535.1 → XP_063137605.1  RNA-binding Raly-like protein isoform X8

    Nucleotide Protein Strain
    Heading Accession and Version

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