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    Hykk hydroxylysine kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300723, updated on 27-Dec-2024

    Summary

    Official Symbol
    Hykkprovided by RGD
    Official Full Name
    hydroxylysine kinaseprovided by RGD
    Primary source
    RGD:1308677
    See related
    EnsemblRapid:ENSRNOG00000013419 AllianceGenome:RGD:1308677
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Agphd1; RGD1308677
    Summary
    Predicted to enable hydroxylysine kinase activity. Predicted to be located in cytoplasm. Orthologous to human HYKK (hydroxylysine kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 645.5) and Liver (RPKM 51.4) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hykk in Genome Data Viewer
    Location:
    8q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (64212043..64235809)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (55315919..55339720)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (59507975..59531745)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit B4, pseudogene 5 Neighboring gene iron responsive element binding protein 2 Neighboring gene proteasome 20S subunit alpha 4 Neighboring gene cholinergic receptor nicotinic alpha 5 subunit Neighboring gene zinc finger CCCH-type containing 15, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables amino acid kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydroxylysine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    hydroxylysine kinase
    Names
    aminoglycoside phosphotransferase domain containing 1
    aminoglycoside phosphotransferase domain-containing protein 1
    NP_001100293.1
    XP_006243134.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106823.1NP_001100293.1  hydroxylysine kinase

      See identical proteins and their annotated locations for NP_001100293.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      A0A8I5Y5E0, A6J4N2, D3ZUX1
      Related
      ENSRNOP00000018003.5, ENSRNOT00000018003.7
      Conserved Domains (1) summary
      PRK06148
      Location:13354
      PRK06148; hypothetical protein; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      64212043..64235809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006243072.4XP_006243134.1  hydroxylysine kinase isoform X1

      See identical proteins and their annotated locations for XP_006243134.1

      UniProtKB/TrEMBL
      A0A8I5Y5E0, A6J4N2, D3ZUX1
      Conserved Domains (1) summary
      PRK06148
      Location:13354
      PRK06148; hypothetical protein; Provisional