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    Capza1b capping actin protein of muscle Z-line subunit alpha 1B [ Mus musculus (house mouse) ]

    Gene ID: 66747, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Capza1bprovided by MGI
    Official Full Name
    capping actin protein of muscle Z-line subunit alpha 1Bprovided by MGI
    Primary source
    MGI:MGI:1913997
    See related
    Ensembl:ENSMUSG00000055357 AllianceGenome:MGI:1913997
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933400A11Rik
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization; barbed-end actin filament capping; and cell junction assembly. Predicted to be part of F-actin capping protein complex and WASH complex. Predicted to be active in cortical cytoskeleton. Orthologous to human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 4.5) See more
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    Genomic context

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    See Capza1b in Genome Data Viewer
    Location:
    X F5; X 79.23 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (168559374..168562631, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (169776378..169779635, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene 15245 Neighboring gene STARR-seq mESC enhancer starr_48283 Neighboring gene predicted gene, 25651 Neighboring gene midline 1 Neighboring gene STARR-seq mESC enhancer starr_48284 Neighboring gene predicted gene, 54065 Neighboring gene RIKEN cDNA G530011O06 gene Neighboring gene STARR-positive B cell enhancer mm9_chrX:166407829-166408130 Neighboring gene STARR-positive B cell enhancer mm9_chrX:166408204-166408505 Neighboring gene STARR-positive B cell enhancer mm9_chrX:166410801-166411102 Neighboring gene STARR-positive B cell enhancer mm9_chrX:166413309-166413610 Neighboring gene STARR-positive B cell enhancer mm9_chrX:166414802-166415103 Neighboring gene STARR-positive B cell enhancer mm9_chrX:166415421-166415722

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Other Names

    • capping protein (actin filament) muscle Z-line, alpha 1 pseudogene

    Clone Names

    • MGC130179, MGC130180

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in barbed-end actin filament capping IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell junction assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of F-actin capping protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of WASH complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cortical cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003635.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AK016585
      Related
      ENSMUST00000068874.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      168559374..168562631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_025743.2: Suppressed sequence

      Description
      NM_025743.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein Strain
    Heading Accession and Version

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