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    Ankrd29 ankyrin repeat domain 29 [ Mus musculus (house mouse) ]

    Gene ID: 225187, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd29provided by MGI
    Official Full Name
    ankyrin repeat domain 29provided by MGI
    Primary source
    MGI:MGI:2687055
    See related
    Ensembl:ENSMUSG00000057766 AllianceGenome:MGI:2687055
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm95; G630054C21; G630054C21Rik
    Summary
    Orthologous to human ANKRD29 (ankyrin repeat domain 29). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 4.1), frontal lobe adult (RPKM 4.0) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ankrd29 in Genome Data Viewer
    Location:
    18 A1; 18 6.15 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (12385414..12439067, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (12252357..12306013, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19293 Neighboring gene regulator of MON1-CCZ1 Neighboring gene NPC intracellular cholesterol transporter 1 Neighboring gene STARR-positive B cell enhancer ABC_E2504 Neighboring gene STARR-seq mESC enhancer starr_43833 Neighboring gene ecotropic viral integration site 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_43835 Neighboring gene laminin, alpha 3 Neighboring gene predicted gene, 36232 Neighboring gene STARR-positive B cell enhancer ABC_E8704 Neighboring gene predicted gene 29200

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay. Darakhshan F, et al. Carcinogenesis, 2006 Feb. PMID 16093251
    2. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190371.1 → NP_001177300.1  ankyrin repeat domain-containing protein 29 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK090336, AK162301, BY091192, BY479478
      Consensus CDS
      CCDS50221.1
      UniProtKB/TrEMBL
      D3YTU5, D3YVV3
      Related
      ENSMUSP00000114028.2, ENSMUST00000118525.9
      Conserved Domains (3) summary
      cd00204
      Location:40 → 165
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:50 → 141
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:78 → 109
      ANK; ANK repeat [structural motif]

    2. NM_001360803.1 → NP_001347732.1  ankyrin repeat domain-containing protein 29 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks alternate in-frame exons in the 5' coding region, compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC102248
      Conserved Domains (3) summary
      cd00204
      Location:7 → 128
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:8 → 39
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:112 → 203
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      12385414..12439067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317867.3 → XP_017173356.1  ankyrin repeat domain-containing protein 29 isoform X1

      Conserved Domains (3) summary
      sd00045
      Location:150 → 181
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:122 → 213
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:219 → 270
      Ank_4; Ankyrin repeats (many copies)

    2. XM_017317869.3 → XP_017173358.1  ankyrin repeat domain-containing protein 29 isoform X3

      Conserved Domains (3) summary
      sd00045
      Location:112 → 143
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:117 → 207
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:81 → 132
      Ank_4; Ankyrin repeats (many copies)

    3. XM_017317871.3 → XP_017173360.1  ankyrin repeat domain-containing protein 29 isoform X5

      UniProtKB/TrEMBL
      A0A3Q4EGJ3
      Related
      ENSMUSP00000156996.2, ENSMUST00000234183.2
      Conserved Domains (3) summary
      sd00045
      Location:108 → 139
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:80 → 171
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:177 → 228
      Ank_4; Ankyrin repeats (many copies)

    4. XM_017317870.3 → XP_017173359.1  ankyrin repeat domain-containing protein 29 isoform X4

      Conserved Domains (3) summary
      sd00045
      Location:145 → 176
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:117 → 208
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:214 → 265
      Ank_4; Ankyrin repeats (many copies)

    5. XM_017317868.3 → XP_017173357.1  ankyrin repeat domain-containing protein 29 isoform X2

      Conserved Domains (3) summary
      sd00045
      Location:150 → 181
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:122 → 213
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:219 → 270
      Ank_4; Ankyrin repeats (many copies)

    6. XM_036161089.1 → XP_036016982.1  ankyrin repeat domain-containing protein 29 isoform X6

      Conserved Domains (3) summary
      sd00045
      Location:108 → 139
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:177 → 228
      Ank_4; Ankyrin repeats (many copies)
      pfam12796
      Location:80 → 171
      Ank_2; Ankyrin repeats (3 copies)

    7. XM_036161090.1 → XP_036016983.1  ankyrin repeat domain-containing protein 29 isoform X7

      Conserved Domains (2) summary
      sd00045
      Location:75 → 106
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:80 → 170
      Ank_2; Ankyrin repeats (3 copies)

    8. XM_017317873.3 → XP_017173362.1  ankyrin repeat domain-containing protein 29 isoform X8

      Conserved Domains (3) summary
      COG0666
      Location:79 → 182
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:76 → 110
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:122 → 170
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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