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    Gimap5 GTPase, IMAP family member 5 [ Mus musculus (house mouse) ]

    Gene ID: 317757, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gimap5provided by MGI
    Official Full Name
    GTPase, IMAP family member 5provided by MGI
    Primary source
    MGI:MGI:2442232
    See related
    Ensembl:ENSMUSG00000043505 AllianceGenome:MGI:2442232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D630024P16; E230026N22Rik
    Summary
    This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in spleen adult (RPKM 18.2), lung adult (RPKM 6.7) and 13 other tissues See more
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    Genomic context

    See Gimap5 in Genome Data Viewer
    Location:
    6 B2.3; 6 23.71 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (48723131..48731134)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (48746197..48754200)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48668564-48668753 Neighboring gene GTPase, IMAP family member 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48677906-48678089 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48682931-48683193 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48688984-48689167 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48689235-48689400 Neighboring gene GTPase, IMAP family member 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:48696005-48696158 Neighboring gene STARR-positive B cell enhancer ABC_E10378 Neighboring gene STARR-positive B cell enhancer ABC_E1320 Neighboring gene STARR-seq mESC enhancer starr_15794 Neighboring gene GTPase, IMAP family member 3 Neighboring gene STARR-positive B cell enhancer ABC_E8101 Neighboring gene predicted gene, 30714

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding  
    enables protein binding PubMed 
    Process Evidence Code Pubs
    involved_in T cell homeostasis  
    involved_in myeloid dendritic cell differentiation  
    involved_in negative regulation of T cell activation  
    involved_in negative regulation of apoptotic process  
    involved_in negative regulation of lipid catabolic process  
    involved_in negative regulation of nitric oxide biosynthetic process  
    involved_in negative regulation of type II interferon production  
    involved_in positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  
    involved_in positive regulation of calcium ion transport into cytosol  
    involved_in positive regulation of gamma-delta T cell differentiation  
    involved_in positive regulation of humoral immune response mediated by circulating immunoglobulin  
    involved_in positive regulation of membrane potential  
    involved_in positive regulation of natural killer cell cytokine production  
    involved_in positive regulation of natural killer cell mediated cytotoxicity  
    involved_in regulation of mitochondrial membrane permeability  
    involved_in temperature homeostasis  
    Component Evidence Code Pubs
    located_in lysosomal membrane  
    located_in multivesicular body membrane  

    General protein information

    Preferred Names
    GTPase IMAP family member 5
    Names
    GTPase of the immunity-associated protein 5
    immunity-associated nucleotide 4-like 1 protein
    immunity-associated protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175035.5NP_778200.1  GTPase IMAP family member 5

      See identical proteins and their annotated locations for NP_778200.1

      Status: REVIEWED

      Source sequence(s)
      AC115045, AC153894
      Consensus CDS
      CCDS20114.1
      UniProtKB/Swiss-Prot
      Q501L7, Q549X3, Q8BWF2
      Related
      ENSMUSP00000056820.6, ENSMUST00000055558.6
      Conserved Domains (1) summary
      pfam04548
      Location:27227
      AIG1; AIG1 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      48723131..48731134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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