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    Or5ac25 olfactory receptor family 5 subfamily AC member 25 [ Mus musculus (house mouse) ]

    Gene ID: 404311, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Or5ac25provided by MGI
    Official Full Name
    olfactory receptor family 5 subfamily AC member 25provided by MGI
    Primary source
    MGI:MGI:3030043
    See related
    Ensembl:ENSMUSG00000095706 AllianceGenome:MGI:3030043
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr207; Olfr208; Olfr209; MOR182-6; MOR182-9
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or5ac25 in Genome Data Viewer
    Location:
    16; 16 C1.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (59181587..59182603, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (59361224..59362240, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AC member 23 Neighboring gene olfactory receptor family 5 subfamily AC member 24 Neighboring gene predicted gene, 33611 Neighboring gene gamma-aminobutyric acid type A receptor subunit rho 3 Neighboring gene STARR-positive B cell enhancer mm9_chr16:59420656-59420957 Neighboring gene ORAI calcium release-activated calcium modulator 2, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Sensitivity-dependent hierarchical receptor codes for odors. Hamana H, et al. Chem Senses, 2003 Feb. PMID 12588732
    2. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding. Sato T, et al. Sci Rep, 2015 Sep 11. PMID 26361056, Free PMC Article
    3. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
    4. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    5. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor 209
    Names
    GA_x54KRFPKG5P-55570276-55569359
    GA_x54KRFPKG5P-55580232-55579315
    GA_x54KRFPKG5P-55590495-55589578
    olfactory receptor 207
    olfactory receptor 208
    olfactory receptor MOR182-6
    olfactory receptor MOR182-9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011792.1 → NP_001011792.1  olfactory receptor 209

      See identical proteins and their annotated locations for NP_001011792.1

      Status: PROVISIONAL

      Source sequence(s)
      AY317292
      UniProtKB/TrEMBL
      Q7TS34, Q7TS36, Q8VF32

    2. NM_207551.2 → NP_997434.2  olfactory receptor 209

      Status: VALIDATED

      Source sequence(s)
      AC154854
      Consensus CDS
      CCDS57032.1
      UniProtKB/TrEMBL
      L7N1X3, Q7TS34
      Related
      ENSMUSP00000053192.4, ENSMUST00000055868.4
      Conserved Domains (2) summary
      cd14964
      Location:25 → 51
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:24 → 302
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      59181587..59182603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249170.1 → XP_030105030.1  olfactory receptor 209 isoform X1

      Consensus CDS
      CCDS84247.1
      UniProtKB/TrEMBL
      A0A140LIQ3, B9EJS4
      Related
      ENSMUSP00000146910.2, ENSMUST00000208246.2
      Conserved Domains (2) summary
      cd14964
      Location:25 → 51
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:24 → 94
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001347243.1: Suppressed sequence

      Description
      NM_001347243.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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