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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001017405.3 → NP_001017405.1 E3 ubiquitin-protein transferase MAEA isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AK001088, AK091951, BC001225, BU607457
- Consensus CDS
-
CCDS33936.1
- UniProtKB/Swiss-Prot
- O95285, Q5JB54, Q6ZRD6, Q7L5Y9, Q9BQ11, Q9H9V6, Q9H9Z4, Q9NW84
- UniProtKB/TrEMBL
-
B4DUB2
- Related
- ENSP00000302830.4, ENST00000303400.9
- Conserved Domains (3) summary
-
- smart00667
Location:120 → 153
- LisH; Lissencephaly type-1-like homology motif
- cd16659
Location:336 → 383
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
- pfam10607
Location:160 → 301
- CLTH; CTLH/CRA C-terminal to LisH motif domain
-
NM_001297430.2 → NP_001284359.1 E3 ubiquitin-protein transferase MAEA isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
- Source sequence(s)
-
AK091951, AK296174, BU607457, DC331820
- UniProtKB/TrEMBL
-
B4DJP8
- Conserved Domains (2) summary
-
- pfam10607
Location:92 → 233
- CLTH; CTLH/CRA C-terminal to LisH motif domain
- cd16659
Location:268 → 315
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
-
NM_001297431.2 → NP_001284360.1 E3 ubiquitin-protein transferase MAEA isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) has multiple differences in the coding region, which results in an internal frameshifted segment, compared to variant 1. The encoded isoform (4) is shorter and has a distinct internal segment, compared to isoform 1.
- Source sequence(s)
-
AK022515, AY236486, BU607457, DC331820
- Consensus CDS
-
CCDS77887.1
- UniProtKB/TrEMBL
-
D6RIB6
- Related
- ENSP00000427512.1, ENST00000514708.5
- Conserved Domains (2) summary
-
- smart00667
Location:120 → 152
- LisH; Lissencephaly type-1-like homology motif
- pfam13445
Location:272 → 311
- zf-RING_UBOX; RING-type zinc-finger
-
NM_001297432.2 → NP_001284361.1 E3 ubiquitin-protein transferase MAEA isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (5) has a shorter and distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK091951, AK301155, BU607457, DC400017
- Consensus CDS
-
CCDS75090.1
- UniProtKB/TrEMBL
- B4DUB2, B4DVN3
- Related
- ENSP00000426807.1, ENST00000510794.5
- Conserved Domains (5) summary
-
- smart00667
Location:119 → 152
- LisH; Lissencephaly type-1-like homology motif
- smart00668
Location:158 → 215
- CTLH; C-terminal to LisH motif
- smart00757
Location:211 → 303
- CRA; CT11-RanBPM
- pfam10607
Location:159 → 300
- CLTH; CTLH/CRA C-terminal to LisH motif domain
- pfam13445
Location:339 → 378
- zf-RING_UBOX; RING-type zinc-finger
-
NM_001297433.2 → NP_001284362.1 E3 ubiquitin-protein transferase MAEA isoform 6
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR, lacks part of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (6) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC078852, AK091951, AK298944, BU607457, DC299400
- Consensus CDS
-
CCDS77888.1
- UniProtKB/TrEMBL
- B4DQT1, B4DUB2
- Related
- ENSP00000424436.1, ENST00000505839.1
- Conserved Domains (3) summary
-
- smart00667
Location:72 → 105
- LisH; Lissencephaly type-1-like homology motif
- cd16659
Location:288 → 335
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
- pfam10607
Location:112 → 253
- CLTH; CTLH/CRA C-terminal to LisH motif domain
-
NM_005882.5 → NP_005873.2 E3 ubiquitin-protein transferase MAEA isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
- Source sequence(s)
-
AK022586, AK091951, BU607457
- Consensus CDS
-
CCDS33937.1
- UniProtKB/TrEMBL
-
B4DUB2
- Related
- ENSP00000264750.6, ENST00000264750.10
- Conserved Domains (3) summary
-
- smart00668
Location:125 → 175
- CTLH; C-terminal to LisH motif
- cd16659
Location:295 → 342
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
- pfam10607
Location:151 → 260
- CLTH; CTLH/CRA C-terminal to LisH motif domain
RNA
-
NR_123716.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks two internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK091951, AY236486, BU607457, DC331820
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12 Reference GRCh38.p14 Primary Assembly
- Range
-
1289891..1340137
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006713849.3 → XP_006713912.1 E3 ubiquitin-protein transferase MAEA isoform X1
- UniProtKB/TrEMBL
-
E7ESC7
- Conserved Domains (3) summary
-
- smart00667
Location:120 → 153
- LisH; Lissencephaly type-1-like homology motif
- cd16659
Location:336 → 365
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
- pfam10607
Location:160 → 301
- CLTH; CTLH/CRA C-terminal to LisH motif domain
-
XM_047449494.1 → XP_047305450.1 E3 ubiquitin-protein transferase MAEA isoform X4
- UniProtKB/TrEMBL
-
D6REW7
- Related
- ENSP00000421644.1, ENST00000503653.5
-
XM_047449495.1 → XP_047305451.1 E3 ubiquitin-protein transferase MAEA isoform X5
-
XM_047449493.1 → XP_047305449.1 E3 ubiquitin-protein transferase MAEA isoform X3
-
XM_006713850.3 → XP_006713913.1 E3 ubiquitin-protein transferase MAEA isoform X2
- Conserved Domains (3) summary
-
- smart00667
Location:119 → 152
- LisH; Lissencephaly type-1-like homology motif
- cd16659
Location:335 → 364
- RING-Ubox_Emp; U-box domain, a modified RING finger, found in erythroblast macrophage protein (Emp) and similar proteins
- pfam10607
Location:159 → 300
- CLTH; CTLH/CRA C-terminal to LisH motif domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1 Alternate T2T-CHM13v2.0
- Range
-
1288439..1338753
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054348721.1 → XP_054204696.1 E3 ubiquitin-protein transferase MAEA isoform X1
- UniProtKB/TrEMBL
-
E7ESC7
-
XM_054348724.1 → XP_054204699.1 E3 ubiquitin-protein transferase MAEA isoform X4
- UniProtKB/TrEMBL
-
D6REW7
-
XM_054348725.1 → XP_054204700.1 E3 ubiquitin-protein transferase MAEA isoform X5
-
XM_054348723.1 → XP_054204698.1 E3 ubiquitin-protein transferase MAEA isoform X3
-
XM_054348722.1 → XP_054204697.1 E3 ubiquitin-protein transferase MAEA isoform X2