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    camk1ga calcium/calmodulin-dependent protein kinase IGa [ Danio rerio (zebrafish) ]

    Gene ID: 335654, updated on 9-Dec-2024

    Summary

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    Official Symbol
    camk1gaprovided by ZNC
    Official Full Name
    calcium/calmodulin-dependent protein kinase IGaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7594
    See related
    Ensembl:ENSDARG00000044526 AllianceGenome:ZFIN:ZDB-GENE-030131-7594
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    camk1g; zgc:73127; wu:fk53c02
    Summary
    Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human CAMK1G (calcium/calmodulin dependent protein kinase IG). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See camk1ga in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (1045277..1069407)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (1032469..1052509)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene peroxisome proliferator-activated receptor delta a Neighboring gene si:ch73-352p18.4 Neighboring gene laminin subunit beta 3 Neighboring gene guanylate cyclase activator 1Ab.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages. Cardoso JC, et al. J Mol Endocrinol, 2016 Jul. PMID 27220618
    2. Lef1-dependent hypothalamic neurogenesis inhibits anxiety. Xie Y, et al. PLoS Biol, 2017 Aug. PMID 28837622, Free PMC Article
    3. Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required. Kopp R, et al. Physiol Genomics, 2010 Sep. PMID 20571107
    4. The vertebrate ancestral repertoire of visual opsins, transducin alpha subunits and oxytocin/vasopressin receptors was established by duplication of their shared genomic region in the two rounds of early vertebrate genome duplications. Lagman D, et al. BMC Evol Biol, 2013 Nov 2. PMID 24180662, Free PMC Article
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium/calmodulin-dependent protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium/calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    calcium/calmodulin-dependent protein kinase IGa
    Names
    calcium/calmodulin-dependent protein kinase IG
    NP_956260.1
    XP_021324979.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199966.1 → NP_956260.1  calcium/calmodulin-dependent protein kinase IGa

      See identical proteins and their annotated locations for NP_956260.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059490
      UniProtKB/TrEMBL
      A0A8M1PG68, Q6PC33
      Related
      ENSDARP00000065379.3, ENSDART00000065380.4
      Conserved Domains (1) summary
      cd14166
      Location:17 → 300
      STKc_CaMKI_gamma; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type I gamma

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      1045277..1069407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469304.2 → XP_021324979.1  calcium/calmodulin-dependent protein kinase IGa isoform X1

      UniProtKB/TrEMBL
      A0A8M1PG68, Q6PC33
      Conserved Domains (1) summary
      cd14166
      Location:17 → 300
      STKc_CaMKI_gamma; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type I gamma
    Nucleotide Protein Strain
    Heading Accession and Version

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