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    l3mbtl3 L3MBTL histone methyl-lysine binding protein 3 [ Danio rerio (zebrafish) ]

    Gene ID: 403075, updated on 9-Dec-2024

    Summary

    Official Symbol
    l3mbtl3provided by ZNC
    Official Full Name
    L3MBTL histone methyl-lysine binding protein 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040724-127
    See related
    Ensembl:ENSDARG00000025983 AllianceGenome:ZFIN:ZDB-GENE-040724-127
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-45m15.2
    Summary
    Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human L3MBTL3 (L3MBTL histone methyl-lysine binding protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See l3mbtl3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (2127479..2177856)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (2100773..2151150)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene enoyl-[acyl-carrier-protein] reductase, mitochondrial Neighboring gene Rho GTPase activating protein 18 Neighboring gene uncharacterized LOC137488607 Neighboring gene transmembrane protein 244 Neighboring gene transmembrane protein 200A Neighboring gene si:ch73-18b11.2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lethal(3)malignant brain tumor-like protein 3
    Names
    CH211-45M15.3
    L3MBTL3, histone methyl-lysine binding protein
    l(3)mbt-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001245964.1NP_001232893.1  lethal(3)malignant brain tumor-like protein 3

      See identical proteins and their annotated locations for NP_001232893.1

      Status: PROVISIONAL

      Source sequence(s)
      BC160626
      UniProtKB/TrEMBL
      B1H1J1
      Related
      ENSDARP00000032665.6, ENSDART00000039249.7
      Conserved Domains (1) summary
      smart00561
      Location:421513
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      2127479..2177856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)