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    sdhaf2 succinate dehydrogenase complex assembly factor 2 [ Danio rerio (zebrafish) ]

    Gene ID: 569482, updated on 9-Dec-2024

    Summary

    Official Symbol
    sdhaf2provided by ZNC
    Official Full Name
    succinate dehydrogenase complex assembly factor 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7564
    See related
    Ensembl:ENSDARG00000062971 AllianceGenome:ZFIN:ZDB-GENE-030131-7564
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj30e04; zgc:163000
    Summary
    Predicted to be involved in aerobic respiration; mitochondrial respiratory chain complex II assembly; and protein-FAD linkage. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SDHAF2 (succinate dehydrogenase complex assembly factor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sdhaf2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (13354627..13362571, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (13101907..13109851, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin VIIb Neighboring gene uncharacterized LOC101883859 Neighboring gene uncharacterized LOC101883820 Neighboring gene si:ch73-119p20.1 Neighboring gene RNA polymerase II, I and III subunit L

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, succinate to ubiquinone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, succinate to ubiquinone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial respiratory chain complex II assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein-FAD linkage IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein-FAD linkage ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in tricarboxylic acid cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    succinate dehydrogenase assembly factor 2, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082864.1NP_001076333.1  succinate dehydrogenase assembly factor 2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001076333.1

      Status: PROVISIONAL

      Source sequence(s)
      BC134190
      UniProtKB/Swiss-Prot
      A3KP74
      Related
      ENSDARP00000086049.5, ENSDART00000091616.8
      Conserved Domains (1) summary
      pfam03937
      Location:60133
      Sdh5; Flavinator of succinate dehydrogenase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      13354627..13362571 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394675.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1809..8708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)