malsu1 mitochondrial assembly of ribosomal large subunit 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: malsu1provided by ZNC
Official Full Name: mitochondrial assembly of ribosomal large subunit 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4956
See related: Ensembl:ENSDARG00000091079 AllianceGenome:ZFIN:ZDB-GENE-030131-4956
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fe14g02; wu:fe14g02; si:zfos-1192g2.3
Summary: Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in negative regulation of ribosome biogenesis and negative regulation of translation. Predicted to be active in mitochondrion. Orthologous to human MALSU1 (mitochondrial assembly of ribosomal large subunit 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (54780544..54782708)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (54906505..54908669)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ribosomal large subunit binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of ribosome biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: mitochondrial assembly of ribosomal large subunit protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001326615.1 → NP_001313544.1 mitochondrial assembly of ribosomal large subunit protein 1

Status: VALIDATED

Source sequence(s)

EH449643, EH544892

UniProtKB/TrEMBL

A0A8M1P8V5, E7F2E7

Related

ENSDARP00000105998.1, ENSDART00000126646.3

Conserved Domains (1) summary

pfam02410
Location:83 → 181

RsfS; Ribosomal silencing factor during starvation