U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    drap1 DR1-associated protein 1 (negative cofactor 2 alpha) [ Danio rerio (zebrafish) ]

    Gene ID: 321681, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    drap1provided by ZNC
    Official Full Name
    DR1-associated protein 1 (negative cofactor 2 alpha)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-400
    See related
    Ensembl:ENSDARG00000041203 AllianceGenome:ZFIN:ZDB-GENE-030131-400
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb26e10; zgc:56003; zgc:77337; wu:fb26e10
    Summary
    Predicted to enable RNA polymerase II general transcription initiation factor activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be part of negative cofactor 2 complex. Predicted to be active in nucleus. Orthologous to human DRAP1 (DR1 associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See drap1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (742512..753232, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (605710..616430, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene neurexin 2b Neighboring gene mitogen-activated protein kinase kinase kinase 11 Neighboring gene zgc:63470 Neighboring gene uncharacterized LOC101883941 Neighboring gene v-rel avian reticuloendotheliosis viral oncogene homolog A

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables core promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of negative cofactor 2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    dr1-associated corepressor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205541.2 → NP_991104.2  dr1-associated corepressor

      Status: VALIDATED

      Source sequence(s)
      CU896668, EH455821
      UniProtKB/TrEMBL
      A0A8M1PEP4, F1R8S0
      Related
      ENSDARP00000060398.4, ENSDART00000060399.6
      Conserved Domains (1) summary
      pfam00808
      Location:11 → 74
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      742512..753232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools