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    bco2a beta-carotene oxygenase 2a [ Danio rerio (zebrafish) ]

    Gene ID: 793849, updated on 9-Dec-2024

    Summary

    Official Symbol
    bco2aprovided by ZNC
    Official Full Name
    beta-carotene oxygenase 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8039
    See related
    Ensembl:ENSDARG00000055722 AllianceGenome:ZFIN:ZDB-GENE-030131-8039
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj48c03; wu:fj48c03
    Summary
    Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. Predicted to be active in mitochondrion. Orthologous to human BCO2 (beta-carotene oxygenase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See bco2a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (30056703..30079480, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (29456463..29479330, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene microRNA let7a-4 Neighboring gene microRNA 125b-2 Neighboring gene succinate dehydrogenase complex, subunit D, integral membrane protein a Neighboring gene translocase of inner mitochondrial membrane 8 homolog B (yeast)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in carotene catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retinal metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    beta-carotene oxygenase 2a; carotenoid-cleaving dioxygenase, mitochondrial
    Names
    beta-carotene oxygenase 2b
    XP_002662060.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      30056703..30079480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002662014.7XP_002662060.4  carotenoid-cleaving dioxygenase, mitochondrial

      UniProtKB/TrEMBL
      A0A8M1RQY3, F1QU45
      Related
      ENSDARP00000113898.2, ENSDART00000133981.3
      Conserved Domains (1) summary
      pfam03055
      Location:58568
      RPE65; Retinal pigment epithelial membrane protein