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    rnf216 ring finger protein 216 [ Danio rerio (zebrafish) ]

    Gene ID: 559441, updated on 4-Jan-2025

    Summary

    Official Symbol
    rnf216provided by ZNC
    Official Full Name
    ring finger protein 216provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-199
    See related
    Ensembl:ENSDARG00000087893 AllianceGenome:ZFIN:ZDB-GENE-081104-199
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-255l18.3
    Summary
    Predicted to enable metal ion binding activity and transferase activity. Acts upstream of or within camera-type eye development and cerebellum development. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Orthologous to human RNF216 (ring finger protein 216). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See rnf216 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (40605124..40664865, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (40463261..40523030, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene actin, beta 2 Neighboring gene fascin actin-bundling protein 1a Neighboring gene urotensin-2 receptor 5 Neighboring gene SMAD specific E3 ubiquitin protein ligase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF216
    XP_068075439.1
    XP_687871.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      40605124..40664865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219338.1XP_068075439.1  E3 ubiquitin-protein ligase RNF216

      UniProtKB/TrEMBL
      A0A8N7TEK8, E7F859
    2. XM_682779.9XP_687871.3  E3 ubiquitin-protein ligase RNF216

      UniProtKB/TrEMBL
      A0A8N7TEK8, E7F859
      Related
      ENSDARP00000117304.1, ENSDART00000138783.2
      Conserved Domains (1) summary
      pfam17061
      Location:77212
      PARM; PARM