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    eif1 eukaryotic translation initiation factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 322237, updated on 9-Dec-2024

    Summary

    Official Symbol
    eif1provided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-956
    See related
    Ensembl:ENSDARG00000012688 AllianceGenome:ZFIN:ZDB-GENE-030131-956
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gc20; eif1b; Sui1-rs1; zgc:56459; zgc:85781; wu:fb54a12; wu:fb64g08; wu:fk63g02
    Summary
    Predicted to enable RNA binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to act upstream of or within translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Orthologous to several human genes including EIF1 (eukaryotic translation initiation factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See eif1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (5418053..5421610)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (5501567..5505124)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene keratin 17 Neighboring gene keratin 91 Neighboring gene uncharacterized LOC137488430 Neighboring gene junction plakoglobin b

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosomal small subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of eukaryotic 43S preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 1
    Names
    eukaryotic translation initiation factor 1B
    suppressor of initiator codon mutations, related sequence 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199588.3NP_955882.1  eukaryotic translation initiation factor 1

      See identical proteins and their annotated locations for NP_955882.1

      Status: VALIDATED

      Source sequence(s)
      BC067620, BI844805, EB970795
      UniProtKB/TrEMBL
      Q6NWE7, Q7ZUI8
      Related
      ENSDARP00000114512.2, ENSDART00000132874.3
      Conserved Domains (1) summary
      cl00229
      Location:3113
      eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      5418053..5421610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)