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    krcp kelch repeat-containing protein [ Danio rerio (zebrafish) ]

    Gene ID: 323406, updated on 9-Dec-2024

    Summary

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    Official Symbol
    krcpprovided by ZNC
    Official Full Name
    kelch repeat-containing proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2126
    See related
    Ensembl:ENSDARG00000040224 AllianceGenome:ZFIN:ZDB-GENE-030131-2126
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb97e08; wu:fi38d02; zgc:123032
    Summary
    Is expressed in several structures, including gut epithelium; hematopoietic system; nervous system; posterior lateral mesoderm; and tail bud. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See krcp in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24881691..24888634)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (24610493..24617477)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885004 Neighboring gene adenosine deaminase domain containing 2 Neighboring gene MAP/microtubule affinity-regulating kinase 2b Neighboring gene REST corepressor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis. Baumgart M, et al. Aging Cell, 2014 Dec. PMID 25059688, Free PMC Article
    2. Combinatorial regulation of novel erythroid gene expression in zebrafish. Galloway JL, et al. Exp Hematol, 2008 Apr. PMID 18243489, Free PMC Article
    3. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Galloway JL, et al. Dev Cell, 2005 Jan. PMID 15621534
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123032

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    kelch repeat-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012366.1 → NP_001012366.1  kelch repeat-containing protein

      See identical proteins and their annotated locations for NP_001012366.1

      Status: PROVISIONAL

      Source sequence(s)
      AY835383
      UniProtKB/TrEMBL
      Q5I9I6
      Related
      ENSDARP00000058842.5, ENSDART00000058843.7
      Conserved Domains (5) summary
      smart00612
      Location:445 → 487
      Kelch; Kelch domain
      sd00038
      Location:323 → 369
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:377 → 410
      Kelch_1; Kelch motif
      pfam13415
      Location:227 → 279
      Kelch_3; Galactose oxidase, central domain
      pfam13418
      Location:270 → 315
      Kelch_4; Galactose oxidase, central domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24881691..24888634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172254.5 → XP_005172311.1  kelch repeat-containing protein isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJM3
      Conserved Domains (5) summary
      smart00612
      Location:446 → 488
      Kelch; Kelch domain
      sd00038
      Location:324 → 370
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:378 → 411
      Kelch_1; Kelch motif
      pfam13415
      Location:228 → 280
      Kelch_3; Galactose oxidase, central domain
      pfam13418
      Location:271 → 316
      Kelch_4; Galactose oxidase, central domain
    Nucleotide Protein Strain
    Heading Accession and Version

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