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    tmsb1 thymosin beta 1 [ Danio rerio (zebrafish) ]

    Gene ID: 798430, updated on 9-Dec-2024

    Summary

    Official Symbol
    tmsb1provided by ZNC
    Official Full Name
    thymosin beta 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8575
    See related
    Ensembl:ENSDARG00000104181 AllianceGenome:ZFIN:ZDB-GENE-030131-8575
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb15g10; tbeta-a; wu:fb15g10; si:dkey-152p16.6
    Summary
    Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Is expressed in gut; intestinal bulb; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tmsb1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (12066698..12071490, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (11760684..11765476, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 711 Neighboring gene zgc:66447 Neighboring gene phosphoribosyl pyrophosphate synthetase 1B Neighboring gene potassium channel tetramerisation domain containing 12b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin monomer binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sequestering of actin monomers IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thymosin beta 1
    Names
    beta thymosin-like protein 2
    thymosin beta-a
    zTB1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001165918.2NP_001159390.1  thymosin beta 1

      See identical proteins and their annotated locations for NP_001159390.1

      Status: VALIDATED

      Source sequence(s)
      BC142834, EH506469, EH532625
      UniProtKB/TrEMBL
      A0A097, C7G093
      Related
      ENSDARP00000130996.1, ENSDART00000165581.2
      Conserved Domains (1) summary
      pfam01290
      Location:341
      Thymosin; Thymosin beta-4 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      12066698..12071490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394896.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      180143..184935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)