zgc:162941 zgc:162941 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:162941provided by ZNC
Official Full Name: zgc:162941provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8517
See related: Ensembl:ENSDARG00000071701 AllianceGenome:ZFIN:ZDB-GENE-030131-8517
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb14a09; wu:fb14a09
Summary: Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to act upstream of or within defense response to bacterium; killing of cells of another organism; and peptidoglycan catabolic process. Predicted to be active in extracellular region. Orthologous to several human genes including LYG2 (lysozyme g2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: chromosome: 14

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (20900989..20908030)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (20603744..20610785)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables lysozyme activity	IBA Inferred from Biological aspect of Ancestor more info
enables lysozyme activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-positive bacterium	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within defense response to bacterium	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within killing of cells of another organism	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within peptidoglycan catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular region	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Lysozyme g-like

Names: lyg2

NP_001076289.1

EC 3.2.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082820.1 → NP_001076289.1 Lysozyme g-like

See identical proteins and their annotated locations for NP_001076289.1

Status: PROVISIONAL

Source sequence(s)

BC134159

UniProtKB/TrEMBL

A0A8M1NBU2, A3KP47

Related

ENSDARP00000096987.3, ENSDART00000106209.4

Conserved Domains (2) summary

COG0741
Location:33 → 157

MltE; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]

cd01021
Location:19 → 183

GEWL; Goose Egg White Lysozyme domain. Eukaryotic "goose-type" lysozymes (GEWL). These enzymes catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc). Members include tunicate, Japanese ...