uqcc3 ubiquinol-cytochrome c reductase complex assembly factor 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: uqcc3provided by ZNC
Official Full Name: ubiquinol-cytochrome c reductase complex assembly factor 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8451
See related: Ensembl:ENSDARG00000093382 AllianceGenome:ZFIN:ZDB-GENE-030131-8451
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb12b10; wu:fb12b10; si:dkey-88p24.9
Summary: Predicted to enable cardiolipin binding activity and phosphatidic acid binding activity. Predicted to be involved in cristae formation; mitochondrial electron transport, ubiquinol to cytochrome c; and mitochondrial respiratory chain complex III assembly. Predicted to act upstream of or within ATP biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 9. Orthologous to human UQCC3 (ubiquinol-cytochrome c reductase complex assembly factor 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (27006266..27009584, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (27044553..27047871, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb12b10.x1 (e-PCR)
- UniSTS:190062

fb12b10.x1 (e-PCR)
- UniSTS:190063

AI384258 (e-PCR)
- UniSTS:206735

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cardiolipin binding	ISS Inferred from Sequence or Structural Similarity more info
enables phosphatidic acid binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within ATP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cristae formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mitochondrial respiratory chain complex III assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex III assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ubiquinol-cytochrome-c reductase complex assembly factor 3

Names: UPF0723 protein C11orf83 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.